Sökning: "Chalcones"

Hittade 1 avhandling innehållade ordet Chalcones.

  1. 1. Design and Synthesis of Chalcone and Chromone Derivatives as Novel Anticancer Agents

    Författare :Christine Dyrager; Göteborgs universitet.; Gothenburg University.; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chalcones; Chromones; Fluorescence; Fluorophore; Cellular imaging; Anticancer; Tubulin; Microtubule; Kinase inhibitors; p38; MEK1; Palladium-mediated reactions; Molecular modeling; Structure-Activity Relationships.;

    Sammanfattning : This thesis comprises the design and synthesis of chalcone and chromone derivatives and their use in various biological applications, particularly as anticancer agents (targeting proteins associated with cancer pathogenesis) and as potential fluorophores for live-cell imaging. Conveniently, all structures presented were synthesized from commercially available 2 ́-hydroxyacetophenones. LÄS MER