Sökning: "Chagas´disease"

Visar resultat 1 - 5 av 15 avhandlingar innehållade ordet Chagas´disease.

  1. 1. Experimental chagas disease

    Författare :John Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Trypanosoma cruzi; NK cells; cytotoxicity; IFN-gamma; IL-12; IFN-alpha beta; Chagas disease; polymyositis; myocarditis; genotype dependence and Toll-like receptors.;

    Sammanfattning : The main focus of this thesis was to develop and utilise experimental models using the protozoan parasite Trypanosoma cruzi. We were especially interested in studying the activation of NK cells early after T. cruzi infection and what factors that predispose to a chronic inflammatory disease after T. cruzi infection. LÄS MER

  2. 2. Immunopathogenesis of experimental Chagas' disease

    Författare :Dan Sunnemark; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Trypanosoma cruzi; Chagas disease; pathology; cytokines; vasculitis; atherosclerosis;

    Sammanfattning : Chagas' disease is a serious, life-threatening disease caused by the protozoan parasite Trypanosoma cruzi in South and Central America. Neither vaccine candidate(s) nor efficient, nontoxic chemotherapeutical agents exist at the present time. LÄS MER

  3. 3. Ecology and Control of Triatomine (Hemiptera: Reduviidae) Vectors of Chagas Disease in Guatemala, Central America

    Författare :Maria Carlota Monroy; Thomas G.T. Jaenson; Chris Curtis; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; Biology; Chagas disease; control; epidemiology; ecology; Triatoma dimidiata; T. nitida; T. ryckmani; Rhodnius prolixus; serology; populations movements; geographic distribution.; Biologi; Biology; Biologi;

    Sammanfattning : This thesis analyses several factors affecting the control of triatomines in Guatemala. There are three synantropic triatomines in Guatemala, i.e., Rhodnius prolixus, Triatoma dimidiata and T. LÄS MER

  4. 4. Mapping the genome and characterization of an acetyltransferase of Trypanosoma cruzi

    Författare :Stephen O Ochaya; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Trypanosoma cruzi; Chagas´disease; karyotyping; genomic; acetyltransferase;

    Sammanfattning : Trypanosoma cruzi (T.cruzi) is a flagellate protozoan parasite that causes Chagas' disease and is most common in Latin American countries. The disease currently infects over 13 million persons and about 100 million more are at risk. Despite basic research for many years, there is neither a vaccine nor useful drugs available to combat the disease. LÄS MER

  5. 5. Detection and characterization of novel proteins in Trypanosoma cruzi

    Författare :Marcela Ferella; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Trypanosoma cruzi is a flagellated protozoan parasite. It infects a wide range of mammals, including humans. Human T. cruzi infections are endemic to South and Central America. LÄS MER