Sökning: "Ceroid"

Hittade 3 avhandlingar innehållade ordet Ceroid.

1. 1. Mechanisms of lipofuscin/ceroid accumulation and its impact on the function of the lysosomal system

   Författare :Alexei Terman; Thomas von Zglinicki; Linköpings universitet; []
   Nyckelord :Aging; Autophagocytosis; Centrophenoxine; Ceroid; Lipofuscin; Lysosomes; Oxidative stress; MEDICINE; MEDICIN;

   Sammanfattning : The accumulation of lipofuscin - an electron-dense, autofluorescent, polymeric, intralysosomal substance - is a recognized hallmark of aging postmitotic cells. Ceroid- a substance very close, or perhaps even identical, to lipofuscin - is a characteristic of various pathological processes, such as lysosomal storage diseases, malnutrition, atherosclerosis, oxidative stress, ionizing radiation, etc. LÄS MER

3. 2. Lysosomal stability under the influence of oxidative stress and lipofuscin accumulation

   Författare :Evalill Nilsson; Ulf Brunk; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN; Medicin;

   Sammanfattning : The lysosome is the cellular organelle responsible for degradation and recycling of macromolecules through hetero- and autophagocytosis. It is generally considered a stable organelle that breaks down only late during cellular degeneration. LÄS MER

4. 3. Characterization of Eae4 and Eae19-22 in autoimmune neuroinflammation

   Författare :Rita Nohra; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :QTL; EAE; MS; epistasis; AIL.;

   Sammanfattning : Multiple Sclerosis (MS) is the most common chronic inflammatory disorders of the central nervous system (CNS) with a prevalence of 1-211000 in the Northern European population. MS is caused by a combination of environmental factors and multiple genes. LÄS MER