Sökning: "Cerebrospinal fluid"
Visar resultat 11 - 15 av 452 avhandlingar innehållade orden Cerebrospinal fluid.
11. Clinical evaluation of an adjustable cerebrospinal fluid shunt valve
Sammanfattning : Introduction: Shunting systems are implanted for draining cerebrospinal fluid to treat hydrocephalus, intracranial cysts, and idiopathic intracranial hypertension. Most shunt systems include a valve which regulates drainage. A differential pressure valve opens when intracranial pressure exceeds the valve’s opening pressure. LÄS MER
12. Studies of cerebral blood flow and cerebrospinal fluid in childhood acute lymphoblastic leukemia
Sammanfattning : Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and more than 80% of the patients are cured today. Treatment might cause side effects and central nervous system (CNS) irradiation has been replaced by systemic high-dose methotrexate (MTX) and intrathecal (IT) MTX due to the risk of late effects. LÄS MER
13. Microdialysis Sampling of Macro Molecules : Fluid Characteristics, Extraction Efficiency and Enhanced Performance
Sammanfattning : In this thesis, fluid characteristics and sampling efficiency of high molecular weight cut-off microdialysis are presented, with the aim of improving the understanding of microdialysis sampling mechanisms and its performance regarding extraction efficiency of biological fluid and biomarkers.Microdialysis is a well-established clinical sampling tool for monitoring small biomarkers such as lactate and glucose. LÄS MER
14. Development of proteomic methods for studying cerebrospinal fluid proteins involved in Alzheimer´s disease
Sammanfattning : Alzheimer's disease (AD) is the most common cause of dementia in western countries. The main neuropathological findings in the AD brain are senile plaques, neurofibrillary tangles and degeneration of neurons and synapses. LÄS MER
15. Assessment of cerebrospinal fluid system dynamics : novel infusion protocol, mathematical modelling and parameter estimation for hydrocephalus investigations
Sammanfattning : Patients with idiopathic normal pressure hydrocephalus (INPH) have a disturbance in the cerebrospinal fluid (CSF) system. The treatment is neurosurgical – a shunt is placed in the CSF system. The infusion test is used to assess CSF system dynamics and to aid in the selection of patients that will benefit from shunt surgery. LÄS MER