Sökning: "Central"

Visar resultat 16 - 20 av 6962 avhandlingar innehållade ordet Central.

1. 16. Development of 2-Pyridone-based central fragments : Affecting the aggregation of amyloid proteins

   Författare :Magnus Sellstedt; Fredrik Almqvist; Petri Pihko; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; 2-pyridone; central fragment alteration; multi-component reactions; directed diversity-oriented synthesis; peptidomimetics; amyloid; protein aggregation; pilicide; curlicide; Biorganic Chemistry; bioorganisk kemi;

   Sammanfattning : There are many applications of small organic compounds, e.g. as drugs or as tools to study biological systems. Once a compound with interesting biological activity has been found, medicinal chemists typically synthesize small libraries of compounds with systematic differences to the initial “hit” compound. LÄS MER

3. 17. Central nervous system targets for micturition control

   Författare :Rikard Pehrson; Avdelningen för klinisk kemi och farmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; central nervous system; Micturition; 5-HT; GABA; tramadol; NAD-299; CGP62349; apomorphine; cerebral infarction; toxikologi; farmaci; farmakognosi; Farmakologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences;

   Sammanfattning : Normal urine storage and bladder emptying are controlled by the central (CNS) as well as the peripheral nervous system. Dysfunction of these mechanisms can lead to urinary incontinence. Urinary tract dysfunctions have symptomatically been treated mainly with drugs acting peripherally. LÄS MER

4. 18. Anabolic androgenic steroids and central monoaminergic systems : Supratherapeutic doses of nandrolone decanoate affect dopamine and serotonin

   Författare :Carolina Birgner; Lena Bergström; Anna Kindlundh-Högberg; Fred Nyberg; Stefan Brené; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; anabolic androgenic steroids; nandrolone decanoate; dopamine; serotonin; rat; central nervous system; Pharmacology; Farmakologi;

   Sammanfattning : Supratherapeutic doses of anabolic androgenic steroids (AASs) are administered, not only as performance-enhancing drugs in the world of sports, but also in order to modify behaviour. AAS abusers are at risk of developing serious physical and psychological side effects such as dependence and aggressive behaviour. LÄS MER

5. 19. Local or central snow deposits?

   Författare :Karin Reinosdotter; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; VA-teknik; Urban Water Engineering;

   Sammanfattning : Snow handling includes activities such as removing, transporting and dumping the snow, as well as controlling the slipperiness. It is a complex issue that has been widely discussed in the media during the past years. The discussions have been focused mainly on snow deposits and the effect created by de icers. LÄS MER

7. 20. Cognitive erosion and its implications in Alzheimer’s disease

   Författare :Selina Mårdh; Thomas Karlsson; Anders Wallin; Linköpings universitet; []
   Nyckelord :Alzheimer’s disease; longitudinal study; mixed methods design; semantic memory; awareness; metacognition; central coherence; emotions; Alzheimers sjukdom; longitudinell studie; mixed methods design; semantiskt minne; medvetande; metakognition; central koherens; emotioner; Do Psychology;

   Sammanfattning : The aim of the present thesis was twofold, first to map the semantic memory decline in Alzheimer patients over time, second to take the patient’s perspective and create a multifaceted picture of the individual with Alzheimer’s disease through the study of memory, awareness, central coherence and emotions. Further issues concerned how Alzheimer individuals handled their cognitive erosion in everyday life and if they were well calibrated with their spouse in disease related matters. LÄS MER