Sökning: "Cell-based biosensor"

Visar resultat 6 - 6 av 6 avhandlingar innehållade orden Cell-based biosensor.

  1. 6. Characterization of HCV Protease Inhibitors : Inhibition and Interaction Studies with Applications for Drug Discovery

    Författare :Sofia Svahn Gustafsson; U. Helena Danielson; Johan Neyts; Uppsala universitet; []
    Nyckelord :Biokemi; Biochemistry;

    Sammanfattning : In this thesis, different approaches based on inhibition and interactions studies, have been used to characterize inhibitors of the non-structural protein 3 (NS3) from the hepatitis C virus (HCV). This involves identification of enzyme inhibitory effects and characterization of interaction mechanisms and kinetics, as well as effects on replication in a cell based system and serum protein binding. LÄS MER