Sökning: "Cell cultures"

Visar resultat 16 - 20 av 693 avhandlingar innehållade orden Cell cultures.

  1. 16. Articular cartilage proteoglycan biosynthesis and sulfation

    Författare :Chengjuan Qu; Mikko Lammi; Heikki Helminen; Juha Töyräs; Anna-Marja Säämänen; Finland Kuopio University of Kuopio Anatomy Department of Biomedicine; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cartilage; Chondrocytes metabolism; Chondroitin sulfates; Glycosaminoglycans; Osteoarthritis; Proteoglycans; Glucosamine; Sulfation; Biochemistry; biokemi; cellforskning; cell research; Orthopaedics; ortopedi;

    Sammanfattning : Glucosamine (GlcN) and glucosamine sulfate (GS) have been used to treat the patients with osteoarthritis(OA) as a disease-modifying agent. Previousin vitro studies have focused on the effects of GlcN or GSon cartilage metabolism, whereas in vivo studies have investigated their potential for the treatment of OA. LÄS MER

  3. 17. Gene Expression Patterns in a Rat Model of Human Endometrial Adenocarcinoma

    Författare :Sandra Karlsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rat; complex disease; Endometrial adenocarcinoma; gene expression profiling; cDNA microarrays; candidate genes; Molecular biology; Medical sciences;

    Sammanfattning : Endometrial cancer develops from the endometrium of the uterus and is the most common pelvic malignancy diagnosed in women in the western society. Similar to all cancer diseases, endometrial cancer is a disorder that results from complex patterns of genetic and epigenetic alterations involved in the malignant transformation. LÄS MER

  4. 18. Understanding and manipulating primary cell walls in plant cell suspension cultures

    Författare :Felicia Leijon; Vincent Bulone; Katja Salomon Johansen; KTH; []
    Nyckelord :Callose synthase; carbohydrate-binding module; cell wall engineering; cellulose microfibril; cellulose nanocrystal; glycosyltransferase; mass spectrometry; plasmodesmata; Populus; primary cell wall; radiometric assay; spectrophotometric assay; Biotechnology; Bioteknologi;

    Sammanfattning : The cell wall is required for many aspects of plant function and development. It is also an accessible and renewable resource utilized both in unrefined forms and as raw material for further development. Increased knowledge regarding cell wall structure and components will contribute to better utilization of plants and the resources they provide. LÄS MER

  5. 19. Organs-on-chips for the pharmaceutical development process : design perspectives and implementations

    Författare :Jonas Christoffersson; Carl-Fredrik Mandenius; Danny van Noort; Peter Sartipy; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Organs-on-chips; cell culture models; pharmaceutical development; microfluidics;

    Sammanfattning : Organs-on-chips are dynamic cell culture devices created with the intention to mimic organ function in vitro. Their purpose is to assess the toxicity and efficacy of drugs and, as early as possible in the pharmaceutical development process, predict the outcome of clinical trials. LÄS MER

  7. 20. Design and characterization of direct electron transfer based biofuel cells including tests in cell cultures

    Författare :Peter Lamberg; Malmö högskola; []
    Nyckelord :biofuel cell; enzymatic fuel cell; direct electron transfer; cellobiose dehydrogenase; biocompatibility; enzyme kinetics; cell culture;

    Sammanfattning : Enzymatic fuel cells (EFCs) are bioelectronic devices based on redox enzymes, which convert chemical energy into electrical energy via biochemical reactions. A major difficulty to overcome is to successfully connect (using e.g., immobilization) the enzymes to the electrode surface. LÄS MER