Sökning: "Cell compartments"

Visar resultat 1 - 5 av 199 avhandlingar innehållade orden Cell compartments.

  1. 1. Spatiotemporal characterization of the human proteome

    Författare :Diana Mahdessian; Emma Lundberg; Arne Lindqvist; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Spatial proteomics; Spatiotemporal proteomics; Immunofluorescence; Human Protein Atlas; Cell compartments; Single cell proteomics; Cell cycle; Cancer;

    Sammanfattning : Characterizing the molecular components of the basic unit of life; the cell, is crucial for a complete understanding of human biology. The cell is divided into compartments to create a suitable environment for the resident proteins to fulfill their functions. LÄS MER

  3. 2. Cell cycle regulation in cancer: A noncoding perspective

    Författare :Mohamad Ali; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Long Noncoding RNA; lncRNA; Cell cycle; S phase; Mitosis; Checkpoint; Cancer; SCAT7; LY6K-AS;

    Sammanfattning : The cell cycle progression is tightly regulated to ensure error-free cell replication. The complexity of the transcriptional machinery aids to function in a spatiotemporal pattern across different phases and genomic loci. LÄS MER

  4. 3. Studies on Tissue Factor with Focus on Cell Signaling and Cancer

    Författare :Oskar Eriksson; Agneta Siegbahn; Lina Badimon; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tissue Factor; blood coagulation; cell signaling; protease; mass spectrometry; immunohistochemistry; colorectal cancer; apoptosis; Eph receptor; Klinisk kemi; Clinical Chemistry; Molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : This thesis have explored the functions of the protein Tissue Factor (TF), which together with its ligand coagulation factor VII/VIIa (FVII/FVIIa) forms a proteolytic complex that functions in initiation of blood coagulation and activation of cell signaling.In paper I, the mechanisms behind the observation that TF/FVIIa signaling protects cells from apoptosis were further investigated. LÄS MER

  5. 4. Diabetes in 3D : β-cell mass assessments in disease models & evaluation of SPECT based imaging

    Författare :Saba Parween; Ulf Ahlgren; Helena Edlund; Eckhard Lammert; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Optical projection tomography; Diabetes; β-cell mass; disease etiology; 3D imaging; radiotracers; Single photon emission computed tomography; molekylär medicin genetik och patologi ; molecular medicine  genetics and pathology ;

    Sammanfattning : Diabetes is a rapidly growing disease with 415 million affected adults worldwide. The pancreatic endocrine cells, most importantly the insulin producing β-cells, play an important role in regulating blood glucose homeostasis. LÄS MER

  7. 5. Dynamics of Biomembranes and Rheological Properties of Living Cells

    Författare :Peter Berntsen; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cell mechanics; lipid dynamics; cell rheology; biomembranes; water dynamics; relaxations; phospholipids; glass transition;

    Sammanfattning : An ingenious assembly of biomolecules and water constitute what we call biological tissue. The presence of water in this assembly is fundamental for the physiological processes and can make the difference between life and death. LÄS MER