Sökning: "Cell Biology"
Visar resultat 6 - 10 av 2453 avhandlingar innehållade orden Cell Biology.
6. Studies on the Role of Apoptosis in Kidney Diseases
Sammanfattning : Apoptosis is one of the most common types of cell death. Under physiological conditions, it plays an essential role in removal of damaged and potentially harmful cells. Excessive apoptosis has however been linked to a number of diseases including proteinuric kidney disease and DKD, and is believed to enhance the disease progression. LÄS MER
7. Regulatory programs controlling profileration during Drosophila nervous system development
Sammanfattning : The central nervous system (CNS) is the most complex organ in the body, responsible for complex functions, including thinking, reasoning and memory. The CNS contains cells of many different types, often generated in vast numbers. LÄS MER
8. Stochastic modelling and analysis of early mouse development
Sammanfattning : The aim of this thesis is to model and describe dynamical events for biological cells using statistical and mathematical tools. The thesis includes five papers that all relate to stochastic modelling of cells. LÄS MER
9. Effects of domestication related genes on behaviour, physiology and gene expression in chickens
Sammanfattning : Domestication, the process when animals adapt to captivity, tends to modify a whole array of traits towards what has been termed “the domesticated phenotype”, where the domesticated animal differs from its wild ancestor in morphology, physiology, development and behaviour. Physiological traits and behaviours are controlled by genes. LÄS MER
10. High-throughput screening using multicellular tumor spheroids to reveal and exploit tumor-specific vulnerabilities
Sammanfattning : High-throughput drug screening (HTS) in live cells is often a vital part of the preclinical anticancer drug discovery process. So far, two-dimensional (2D) monolayer cell cultures have been the most prevalent model in HTS endeavors. However, 2D cell cultures often fail to recapitulate the complex microenvironments of in vivo tumors. LÄS MER