Sökning: "Celiac disease autoimmunity"
Visar resultat 6 - 9 av 9 avhandlingar innehållade orden Celiac disease autoimmunity.
6. Immunogenetics of Type 1 diabetes and Celiac disease
Sammanfattning : AbstractThe primary purpose of understanding disease etiology is to explain how a specific phenotype is determined by genotype. In pursue of this aim, exploring the diversity in DNA sequence variants that affect biomedical traits, especially those related to the onset and progression of genetically determined human disease. LÄS MER
7. Aspects of infant food factors on intestinal inflammation and effects of probiotics in celiac disease autoimmunity
Sammanfattning : Aims: The overall aim of this thesis was to study dietary components with focus on exposure and ability to affect gutpermeability, peripheral immune response and gut microbiota in children at genetic risk of developing CD. Thespecific aims were to study presence of food components that might induce intestinal inflammation, evaluatepossible effects on intestinal permeability by food emulsifiers, investigate if two different strains of Lactobacillaceaeaffect ongoing CD autoimmunity and gut microbiota composition. LÄS MER
8. The Perfect Storm? Gluten and type 1 diabetes
Sammanfattning : Aim: The general objective of the present research was to study the association between type 1 diabetes and celiac disease, and the effects of dietary gluten on the risk of developing type 1 diabetes. More specific aims were as follows: to estimate the prevalence of celiac-disease-associated autoantibodies in children with type 1 diabetes; to study the connection between non-HLA genetic risk markers and autoantibodies associated with type 1 diabetes and celiac disease during the first year after diagnosis of type 1 diabetes; to investigate the effect of gluten on the risk of developing type 1 diabetes; to evaluate the impact of perinatal factors on the risk of developing both type 1 diabetes and celiac disease. LÄS MER
9. The Clinical and Pathological Spectrum of Idiopathic Inflammatory Myopathies : Implications for pathogenesis, classification and diagnosis
Sammanfattning : Background: Idiopathic inflammatory myopathies (IIM) constitute a heterogeneous group of diseases with severe consequences for the life of affected patients. Dermatomyositis, polymyositis and inclusion body myositis (IBM) are the classical representatives of this group. LÄS MER