Sökning: "Cecilia Persson"

Visar resultat 6 - 10 av 18 avhandlingar innehållade orden Cecilia Persson.

  1. 6. Novel Materials and Implant Designs for the Treatment of Degenerative Disc Disease

    Författare :Salim Ghandour; Cecilia Persson; Donal McNally; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Topology Optimization; Spine; Intervertebral Disc; Papain; Additive Manufacturing; Biomechanics; Bone Cement; PMMA; Calcium Phosphate; Cage; Fusion; Engineering Science with specialization in Biomedical Engineering; Teknisk fysik med inriktning mot medicinsk teknik;

    Sammanfattning : The overarching objective of this thesis was to develop intervertebral implants for degenerated discs through design, fabrication, and mechanical validation. The research had four primary aims, each addressing different facets of implant development. LÄS MER

  3. 7. Effects of Endogenous and Exogenous Hormones on the Female Breast : With Special Reference to the Expression of Proteoglycans

    Författare :Gunilla Hallberg; Tord Naessén; Gunvor Ekman-Ordeberg; Ingemar Persson; Cecilia Magnusson; Eva von Schoultz; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast tissue; proteoglycans; mammographic density; oral contraceptives; androgen receptor; proliferation; apoptosis; extracellular matrix; premenopausal; Obstetrics and gynaecology; Obstetrik och gynekologi; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : This thesis aims to study the effects of endogenous and exogenous hormones and mammographic breast density (BD) on cellular markers in non-cancerous female breast tissue. Women on the waiting list for breast reduction plastic surgery were recruited (n = 79), and randomized to 2 months of hormone therapy or no therapy before surgery. LÄS MER

  4. 8. Functional Aspects of Cranial Implants : Mechanical and Regenerative Properties

    Författare :Susanne Lewin; Caroline Öhman-Mägi; Cecilia Persson; Harry van Lenthe; Uppsala universitet; []
    Nyckelord :Calcium phosphate; Ti-6Al-4V; composites; mechanical properties; finite element methods; cranial implants; computed tomography; quantitative image analysis; Teknisk fysik med inriktning mot materialvetenskap; Engineering Science with specialization in Materials Science;

    Sammanfattning : In several neurosurgical procedures, the skull must be temporarily opened. The resulting bone defect can subsequently be reconstructed with a cranial implant. However, the complication rate of this surgical procedure is high (~20%). The most common complication for cranial implants is infection. LÄS MER

  5. 9. Injectable Biomaterials for Spinal Applications

    Författare :Alejandro López; Cecilia Persson; Håkan Engqvist; Andreas Boger; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; injectable; biomaterials; bone cement; vertebral compression fractures; spine; radiopacity; minimally invasive treatment; low-modulus cement; oligomer; PMMA; calcium phosphate; vertebroplasty; bone; Teknisk fysik med inriktning mot materialvetenskap; Engineering Science with specialization in Materials Science;

    Sammanfattning : The use of injectable biomaterials is growing as the demands for minimally invasive procedures, and more easily applicable implants become higher, but their availability is still limited due to the difficulties associated to their design.Each year, more than 700,000 vertebral compression fractures (VCF’s) are reported in the US and 500,000 VCF’s in Europe due to primary osteoporosis only. LÄS MER

  7. 10. Calcium Phosphate Based Biomaterials for Bone Augmentation

    Författare :Jun Luo; Cecilia Persson; Håkan Engqvist; Marc Bohner; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; bone substitute materials; calcium phosphate cements; apatite; brushite; monetite; setting mechanism; premixed; fibre reinforcement; composite; silk fibroin; mechanical properties; Teknisk fysik med inriktning mot materialvetenskap; Engineering Science with specialization in Materials Science;

    Sammanfattning : Basic (apatite-based) calcium phosphate cements (CPCs), and acidic (brushite and monetite-based) CPCs are used as bone replacement materials because of their bioactivity, mouldability and ability to harden in place. However, their application is limited by their inherent brittleness and difficulties related to their handling. LÄS MER