Sökning: "Cecilia Månsson"

Hittade 1 avhandling innehållade orden Cecilia Månsson.

  1. 1. The Molecular Chaperone DNAJB6 - A Suppressor of Disease Related Amyloid Fibril Formation

    Detta är en avhandling från Department of Chemistry, Lund University

    Författare :Cecilia Månsson; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNAJ; HSP40; molecular chaperones; amyloid fibrils; Alzheimer’s disease; Huntington’s Disease; crosslinking mass spectrometry; chemical kinetics; aggregation; fibril formation;

    Sammanfattning : Several neurodegenerative diseases are caused by peptides or proteins forming amyloid fibrils such as the Aβ peptide involved in Alzheimer’s disease and the huntingtin exon-1 with a prolonged polyglutamine (polyQ) stretch involved in Huntington’s disease. The ability to form amyloid fibrils is an intrinsic feature in all proteins. LÄS MER