Sökning: "Caveolin 3"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden Caveolin 3.

1. 1. Role of caveolin-1 in brown adipose tissue

   Författare :Charlotte L. Mattsson; Barbara Cannon; Paul Pilch; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; caveolin; brown adipose tissue; metabolism; signaling; Physiology; Fysiologi; fysiologi; Physiology;

   Sammanfattning : Caveolae are 50-100 nm invaginations in the plasma membrane. Caveolae and the protein caveolin-1 (Cav1) have been shown to be important in many signaling pathways in different cell types; however, in some cell types caveolae and Cav1 do not seem to affect the investigated signaling pathways. LÄS MER

3. 2. Caveolae associated proteins and how they effect caveolae dynamics

   Författare :Björn Morén; Richard Lundmark; Volker Haucke; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Caveolae; caveolin; EHD2; cavin; microdomain; microscopy; TIRF; AFM; medicinsk biokemi; Medical Biochemistry;

   Sammanfattning : Caveolae are a type of invaginated membrane domain that has been shown to be involved in several disease states, including lipodystrophy, muscular dystrophies and cancer. Several of these diseases are caused by the lack of caveolae or caveolae-related signaling deficiencies in the tissues in which the caveolar domain are abundant such as lung, adipose, muscle and their related endothelial cells. LÄS MER

4. 3. Integration of signalling in smooth muscle caveolae

   Författare :Yulia Shakirova; Cellulär biomekanik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Caveola; caveolin; detrusor; cavin; smooth muscle contractility; remodelling; NO; vascular dysfunction; smooth muscle; erectile dysfunction;

   Sammanfattning : Caveolae and lipid rafts are plasma membrane microdomains that are considered to play a role in cellular signalling. Caveolins and cavins as well as cholesterol are required for the structure and function of caveolae. The papers summarized in this thesis examine the role of caveolae in smooth muscle function. LÄS MER

5. 4. Autosomal Dominant Leukodystrophy with Autonomic Symptoms and Rippling Muscle Disease : Translational Studies of Two Neurogenetic Diseases

   Författare :Jimmy Sundblom; Anja Smits; Raili Raininko; Niklas Dahl; Klas Kullander; Åsa Fex-Svenningsen; Marianne de Visser; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inborn genetic diseases; Leukoencephalopathies; Lamin type B; Muscular disease; Caveolin 3; Neurology; Neurologi;

   Sammanfattning : There is a large variety of diseases caused by single-gene mutations. Although most of these conditions are rare, together they impose a significant burden to the population. LÄS MER

7. 5. Intracellular components involved in parathyroid sensing of extracellular calcium

   Författare :Isaac G. Onyango; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Parathyroid hormone; secretion; Src kinase; ERK; PI 3-kinase; PKC; extracellular calcium; parathyroid cell; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

   Sammanfattning : Parathyroid glands are the primary regulator of extracellular calcium ([Ca2+]e). Ca2+ plays a key role in many fundamental biological processes and is also an essential structural component of the skeleton. The parathyroid chief cells detect small changes in [Ca2+]e and respond by altering the secretion of parathyroid hormone (PTH). LÄS MER