Avancerad sökning

Visar resultat 1 - 5 av 87 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Catabolism of Pyrimidines in Yeast

    Författare :Anna Rasmussen; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Pyrimidine degradation; catabolism of pyrimidines; nucleic acid precursors; yeast; Lachancea kluyveri; URC pathway;

    Sammanfattning : Pyrimidines are important precursors for nucleic acids, and constantly synthesized and degraded in the cell to maintain a balanced supply. Many microoganisms can also extract the nitrogens from the pyrimidine ring, and use them as a nitrogen source when “preferred” sources are absent. LÄS MER

  3. 2. Leptin endocrinology and energy homeostasis in salmonids

    Författare :Marcus Johansson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Leptin; Leptin binding-protein; Energy homeostasis; Oncorhynchus mykiss; Salvelinus alpinus; Adiposity; Food intake; Fasting; Refeeding; Catabolism; Anorexia;

    Sammanfattning : In salmonids, the physiological role of leptin is not completely elucidated. Nonetheless, the anorexigenic effect of leptin indicates a role in their energy homeostasis. This thesis focuses on advancing the understanding of the involvement of the leptin system in the regulation of energy homeo-stasis and food intake in teleost fish. LÄS MER

  4. 3. Endocannabinoid metabolism : the impact of inflammatory factors and pharmacological inhibitors

    Författare :Jessica Karlsson; Christopher Fowler; Stig Jacobsson; Jürg Gertsch; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endocannabinoid; anandamide; 2-AG; fatty acid amide hydrolase; cyclooxygenase-2; prostate cancer; catabolism; inflammation; inflammatory factors;

    Sammanfattning : The endocannabinoid (eCB) system is an endogenous signaling system consisting of ligands (referred to as endocannabinoids, eCBs), receptors and metabolic enzymes. The eCB system is involved in homeostatic control of a variety of biological functions such as neuronal signaling, mood, appetite and pathological conditions such as pain, inflammation and tumour progression. LÄS MER

  5. 4. Multiple regulatory inputs for hierarchical control of phenol catabolism by Pseudomonas putida

    Författare :W. K. Anjana Madhushani; Victoria Shingler; Livia Leoni; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; P. putida; Phenol catabolism; dmpR; dmp-System; 5’-LR; Carbon Catabolite Repression; Transcriptional Translational regulation; Crc; CrcZ; CrcY; Hfq;

    Sammanfattning : Metabolically versatile bacteria have evolved diverse strategies to adapt to different environmental niches and respond to fluctuating physico-chemical parameters. In order to survive in soil and water habitats, they employ specific and global regulatory circuits to integrate external and internal signals to counteract stress and optimise their energy status. LÄS MER

  7. 5. The Role of Proline Catabolism in Candida albicans Pathogenesis

    Författare :Fitz Gerald S. Silao; Per O. Ljungdahl; Joachim Morschhäuser; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Candida albicans; proline metabolism; ATP; P5C; virulence; macrophage; hyphae; filamentation; Ras1 cAMP PKA; mitochondria; Proline dehydrogenase; P5C dehydrogenase; reactive oxygen species; Proline-P5C cycle; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Candida albicans is an opportunistic fungal pathogen that has evolved in close association with human hosts. Pathogenicity is linked to an array of virulence characteristics expressed in response to environmental cues and that reflect the requirement to take up and metabolize nutrients available in the host. LÄS MER