Sökning: "Cars k"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden Cars k.

1. 1. Relation Between Drug Exposure and Selection of Antibiotic Resistant Bacteria

   Författare :Sara K. Olofsson; Otto Cars; Dan I. Andersson; Diarmaid Hughes; George G. Zhanel; Uppsala universitet; []
   Nyckelord :Microbiology; Pharmacokinetics; Pharmacodynamics; Antibiotic resistance; Selection; Transmission; Mathematical model; Escherichia coli; Mikrobiologi;

   Sammanfattning : The worldwide increase in antibiotic resistance is a concern for public health. When the appropriate antibiotic dosage is determined, the priorities are efficacy and toxicity. The aim of this thesis was to gain knowledge about the most efficient dosing regimens in order to minimize the emergence and selection of antibiotic-resistant mutants. LÄS MER

3. 2. Multidrug-Resistant Escherichia coli and Klebsiella pneumoniae : Treatment, Selection and International Spread

   Författare :Thomas Tängdén; Otto Cars; Anders Johansson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Escherichia coli; Klebsiella pneumoniae; extended-spectrum beta-lactamases; carbapenemases; metallo-beta-lactamases; synergy; antibiotic interventions;

   Sammanfattning : The prevalence of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum beta-lactamases (ESBLs) and carbapenemases is increasing worldwide. Therapeutic options for infections with these bacteria are limited not only by the production of ESBLs and carbapenemases, which confer resistance to cephalosporins and carbapenems, but also by frequent co-resistance to other antibiotics. LÄS MER

4. 3. Antibiotic Resistance and Population Dynamics of Escherichia coli in Relation to a Large Scale Antibiotic Consumption Intervention

   Författare :Martin Sundqvist; Otto Cars; Gunnar Kahlmeter; Dan I Andersson; Jordi Vila; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reversibility; trimethoprim; dfr; associated resistance; MLST; Infectious diseases; Infektionssjukdomar; Clinical bacteriology; Klinisk bakteriologi; Medical microbiology; Medicinsk mikrobiologi; Infectious Diseases; Infektionssjukdomar;

   Sammanfattning : Antibiotic resistance challenges the practice and development of modern medicine. The aim of this thesis was to test the hypothesis that antibiotic resistance is reversible once the selection pressure of an antibiotic is removed. LÄS MER

5. 4. Development of Dual-broadband Rotational CARS for Combustion Diagnostics

   Författare :Joakim Bood; Förbränningsfysik; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; N2; O2; C2H2; Dimethyl Ether DME ; High pressure; Stray light filtering; multi-point CARS; CARS; Temperature; Engine knock; Physics; Fysik; Fysicumarkivet A:2000:Bood;

   Sammanfattning : The present thesis concerns development and application of dual-broadband rotational coherent anti-Stokes Raman spectroscopy (DB-RCARS) for temperature and species concentration measurements in combustion processes. Both fundamental development of the technique, including experimental as well as modelling results, and measurements in practical combustion devices were conducted. LÄS MER

7. 5. Rotational Coherent Anti-Stokes Raman Spectroscopy: Experimental and Theoretical Developments in Gas-phase Thermometry

   Författare :Mikael Afzelius; Förbränningsfysik; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; collision line-broadening calculations; combustion laser diagnostics; Laserteknik; Laser technology; CARS; coherent laser spectroscopy; Fysicumarkivet A:2004:Afzelius;

   Sammanfattning : Dual-broadband pure rotational coherent anti-Stokes Raman spectroscopy was investigated in terms of thermometry and species concentration measurement for studies of combustion. The modelling of rotational CARS spectra under conditions of high pressure at room temperature was investigated. LÄS MER