Sökning: "Caroline Heckman"

Hittade 2 avhandlingar innehållade orden Caroline Heckman.

1. 1. Resolving the Genomic Complexity of Pediatric Acute Lymphoblastic Leukemia

   Författare :Yanara Marincevic-Zuniga; Ann-Christine Syvänen; Caroline Heckman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute lymphoblastic leukemia ALL ; 450k array; DNA methylation; RNA-sequencing; linked-read WGS; B-other; fusion gene; chromosomal translocation; Medicinsk genetik; Medical Genetics;

   Sammanfattning : Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer in the Nordic countries. Structural chromosomal rearrangements are a hallmark of ALL and represent key markers for diagnosis, risk stratification and prognosis. LÄS MER

3. 2. Multi-omics analysis of relapsed acute myeloid leukemia

   Författare :Svea Stratmann; Linda Holmfeldt; Caroline Heckman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute myeloid leukemia AML ; relapse and resistance; next generation sequencing WGS WES ; RNA-sequencing; DNA methylation; HiRIEF LC-MS; proteogenomics; Molekylär medicin; Molecular Medicine;

   Sammanfattning : The prognosis for patients suffering from acute myeloid leukemia (AML) remains unsatisfactory and survival is often measured in months. Although the majority of patients achieve complete remission after aggressive treatment, most of them relapse within a few years. LÄS MER