Sökning: "Carmen Basic"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Carmen Basic.
1. Heart failure epidemiology with emphasis on young adults
Sammanfattning : Background: Heart failure (HF) is a major health problem worldwide with exponentially increasing incidence with age and the majority of patients being elderly. In recent years, an increase in hospitalization and prevalence of HF in younger persons has been documented in Sweden and Denmark, in contrast to an overall decrease in older patients. LÄS MER
2. Cancer and Therapy: A look into stemness and the tumour microenvironment
Sammanfattning : Therapy is the often-used treatment for cancer patients, even those that undergo resection surgery. While milestones have been surpassed throughout the decades for a number of cancer types, there are those that comprise of characteristics limiting effectiveness of treatments. LÄS MER
3. Immune evasion and identification of biomarkers associated with mycobacterial infection
Sammanfattning : .... LÄS MER
4. Mycobacterial infection: Immune evasion, host susceptibility and immunological markers of diagnostic importance
Sammanfattning : IIn the first study, we investigated the functional implications of prolonged TLR signalling on IFN-γ mediated killing of mycobacteria by murine macrophages in vitro. TLR2, but not TLR4 ligation interfered with IFN-γ mediated killing of mycobacteria in macrophages. LÄS MER
5. Maturation of humoral immune responses : Studies on the effects of antigen type, apoptosis and age
Sammanfattning : The humoral immune response is dependent on the formation of antibodies. Antibodies are produced by terminally differentiated B cells, plasma cells. Plasma cells are generated either directly from antigen challenged B cells, memory cells or from cells that have undergone the germinal center (GC) reaction. LÄS MER