Sökning: "Carl-Fredrik Burman"

Hittade 2 avhandlingar innehållade orden Carl-Fredrik Burman.

1. 1. A sequential allocation rule

   Författare :Carl-Fredrik Burman; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : .... LÄS MER

3. 2. On Sequential Treatment Allocations in Clinical Trials

   Författare :Carl-Fredrik Burman; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; treatment assignment; clinical trial; biased coin designs; balance of prognostic factors; sequential design; randomization test; expected p-value; deficiency; efficiency; efficiency;

   Sammanfattning : This dissertation treats baseline-dependent sequential designs of two-treatment parallel-group clinical trials. The treatment assignments are chosen in order to minimize the variance, in a linear model, of the treatment effect. This is done for each new allocation using a generalized biased coin design, or a non-randomized minimization' method. LÄS MER