Sökning: "Carl Diehl"

Hittade 1 avhandling innehållade orden Carl Diehl.

1. 1. Conformational Entropy and Protein Flexibility in Drug Design Studied by NMR Spectroscopy

   Författare :Carl Diehl; Biofysikalisk kemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MMP-12; Galectin-3; confomational entropy; order parameters; ITC; Protein dynamics; isothermal titration calorimetry; macrophage elastase; nuclear magnetic resonance; NMR;

   Sammanfattning : Proteins are complex molecules, present in all of the vital functions of life. The function of a protein is regulated by interactions between protein and other molecules. Drug design in pharmaceutical science aims to regulate the function of a protein by the design of synthesized molecules that binds to a protein with high affinity. LÄS MER