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  1. 1. Effects of antiresorptive agents on inflammation and bone regeneration in different osseous sites - experimental and clinical studies

    Författare :Carina Cardemil; Peter Thomsen; Cecilia Larsson Wexell; Bente Brokstad Herlofson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Qntiresorptive agents; ovariectomised rat; osteoporosis; skeletal site; differences osteonecrosis of the jaw; osseointegration; bone substitute; inflammation; bone regeneration; gene expression; histomorphometry; Micro-CT; antiresorptive agents; ovariectomised rat; osteoporosis; skeletal site differences; osteonecrosis of the jaw; osseointegration; bone substitute; inflammation; bone regeneration; gene expression; histomorphometry; Micro-CT;

    Sammanfattning : The biological mechanisms involved in bone regeneration in osteoporotic bone and the effect of antiresorptive drugs in relation to surgically inserted biomaterials are not fully understood. Improved osseointegration of titanium implants but also adverse effects of antiresorptive therapies, such as osteonecrotic jaw have been described in the literature. LÄS MER