Sökning: "Candida antarctica Lipase A"

Visar resultat 1 - 5 av 59 avhandlingar innehållade orden Candida antarctica Lipase A.

  1. 1. Protein Engineering of Candida antarctica Lipase A Enhancing Enzyme Properties by Evolutionary and Semi-Rational Methods

    Detta är en avhandling från Stockholm : Department of Organic Chemistry, Stockholm University

    Författare :Anders G. Sandström; Jan-Erling Bäckvall; Uwe T. Bornscheuer; [2010]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; lipase; protein engineering; directed evolution; kinetic resolution; structural biology; TECHNOLOGY Bioengineering Enzyme engineering; TEKNIKVETENSKAP Bioteknik Enzymteknik; Organic Chemistry; organisk kemi;

    Sammanfattning : Enzymes are gaining increasing importance as catalysts for selective transformations in organic synthetic chemistry. The engineering and design of enzymes is a developing, growing research field that is employed in biocatalysis. LÄS MER

  2. 2. Rational redesign of Candida antarctica lipase B

    Detta är en avhandling från Stockholm : Department of Organic Chemistry, Stockholm University

    Författare :Anders Magnusson; Karl Hult; Bernhard Hauer; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Candida antarctica lipase B; rational redesign; secondary alcohols; substrate-assisted catalysis; S-selective; entropy; aldolase; stereospecificity pocket; oxyanion hole.; Biokemi; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi;

    Sammanfattning : This thesis describes the use of rational redesign to modify the properties of the enzyme Candida antarctica lipase B. Through carefully selected single-point mutations, we were able to introduce substrate-assisted catalysis and to alter the reaction specificity. LÄS MER

  3. 3. Enthalpy and Entropy in Enzyme Catalysis A Study of Lipase Enantioselectivity

    Detta är en avhandling från Stockholm : KTH

    Författare :Jenny Ottosson; [2001]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biocatalysis; enzyme catalysis; Candida antarctica lipase B; enantioselectivity; enthalpy; entropy; CALB; enantiomeric ratio; TECHNOLOGY Bioengineering; TEKNIKVETENSKAP Bioteknik;

    Sammanfattning : Biocatalysis has become a popular technique in organic synthesis due to high activity and selectivity of enzyme catalyzed reactions. Enantioselectivity is a particularly attractive enzyme property, which is utilized for the production of enantiopure substances. LÄS MER

  4. 4. Engineering Candida antarctica Lipase A for Enantioselective Transformations in Organic Synthesis Design, Immobilization and Organic Solvent Screening of Smart Enzyme Libraries

    Detta är en avhandling från Stockholm : Department of Organic Chemistry, Stockholm University

    Författare :Ylva Wikmark; Jan-Erling Bäckvall; Romas Kazlauskas; [2015]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Candida antarctica Lipase A; protein engineering; enzyme libraries; enzyme immobilization; biocatalysis; Organic Chemistry; organisk kemi;

    Sammanfattning : The use of enzymes as catalysts in organic synthesis constitutes an attractive alternative to conventional chemical catalysis. Enzymes are non-toxic and biodegradable and they can operate under mild reaction conditions. LÄS MER

  5. 5. Lipase-Catalyzed Syntheses of Telechelic Polyesters

    Detta är en avhandling från Stockholm : KTH

    Författare :Magnus Eriksson; Karl Hult; Mats Martinelle; Sergio Riva; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Candida antarctica lipase B; lipase-catalysis; polymerization; telechelic; functional polyesters; ring-opening polymerization; polycondensation.; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi;

    Sammanfattning : Telechelic polyesters have successfully been synthesized with lipase-catalyzed polymerization. The produced telechelics had a high degree of di­functionalization, high purity (requiring little or no workup) and controlled degree of polymerization. The syntheses were performed in one-pot one-step reaction systems. LÄS MER