Sökning: "Candida albicans"

Visar resultat 6 - 10 av 43 avhandlingar innehållade orden Candida albicans.

  1. 6. Pharmaceutical And Immunollogical Challenge Of Fungal Pathogens

    Författare :Marios Stylianou; Constantin F. Urban; Christophe d' Enfert; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mast cells; Candida albicans; yeast to hyphal form; antifungal drugs; repurposed drugs; HTS;

    Sammanfattning : Incidences of fungal infections are on the rise in immunosuppressed people. Predominant causative agents for these mycoses are species of the genus Candida, including Candida albicans, Candida glabrata and Candida dublieniensis. Despite a wide range of emerging pathogens, C. albicans remains the leading cause. LÄS MER

  3. 7. D-arabinitol in the diagnosis of invasive candidiasis

    Författare :Gudrun Sigmundsdottir; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; D-arabinitol; D-arabitol; Candida; invasive candidiasis; production rate; diagnosis; neonate; neutropenic; HIV;

    Sammanfattning : Invasive candidiasis (IC) is a serious condition and timely diagnosis with early initiation of antifungal therapy is imerative for improving outcomes. Arabinitol is a sugar alcohol with two stereoisomers, D-arabinitol (DA) and L-arabintiol (LA). LÄS MER

  4. 8. Immunological Studies using Human and Canine Model Disorders

    Författare :Kerstin M. Ahlgren; Anna Lobell; Olle Kämpe; Kerstin Lindblad-Toh; Roland Jonsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoimmunity; T cell; T helper cell; B cell; Autoantibodies; Interferon; Interleukin; Dogs; APS-1; Candida albicans; fungus; Immunologi; Immunology; Medicin; Medicine;

    Sammanfattning : The studies presented in this thesis focus on human and canine models for autoimmune disease, with the main aim to gain new knowledge about disease mechanisms and to further evaluate the dog as a model for autoimmune disease. Autoimmune Polyendocrine Syndrome type 1 (APS-1) is a hereditary human multiorgan disease caused by mutations in the autoimmune regulator (AIRE) gene. LÄS MER

  5. 9. The Role of Proline Catabolism in Candida albicans Pathogenesis

    Författare :Fitz Gerald S. Silao; Per O. Ljungdahl; Joachim Morschhäuser; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Candida albicans; proline metabolism; ATP; P5C; virulence; macrophage; hyphae; filamentation; Ras1 cAMP PKA; mitochondria; Proline dehydrogenase; P5C dehydrogenase; reactive oxygen species; Proline-P5C cycle; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Candida albicans is an opportunistic fungal pathogen that has evolved in close association with human hosts. Pathogenicity is linked to an array of virulence characteristics expressed in response to environmental cues and that reflect the requirement to take up and metabolize nutrients available in the host. LÄS MER

  7. 10. Modulation of neutrophil extracellular trap formation in health and disease

    Författare :Ava Hosseinzadeh; Constantin F. Urban; Carol Munro; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; Candida albicans; Adenosine; Tempol; Nicotine; molekylärbiologi; Molecular Biology;

    Sammanfattning : The critical prompt innate immune response is highly built upon the influx of neutrophils from the blood stream to the site of infection. In the battlefield, neutrophils sense pathogen-associated molecular patterns (PAMPs) through their pattern-recognition receptors (PRRs) to launch a number of responses with the goal to defeat the invading pathogen. LÄS MER