Sökning: "Cancer prevention"

Visar resultat 11 - 15 av 210 avhandlingar innehållade orden Cancer prevention.

1. 11. Genetic epidemiology of prostate cancer

   Författare :Fredrik Wiklund; Henrik Grönberg; Douglas Easton; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; prostate cancer; epidemiology; genetics; linkage analysis; genome-wide scan; Onkologi; Oncology; Onkologi; Oncology; onkologi;

   Sammanfattning : Prostate cancer is a major health burden throughout the world, yet the etiology of prostate cancer is poorly understood. Evidence has accumulated supporting the existence of a hereditary form of this disease. LÄS MER

3. 12. Role of mitochondria in early molecular diagnosis and prognosis of cancer

   Författare :Yanni Li; Allmänmedicin och klinisk epidemiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; mtDNA copy number; mitochondrial-related nuclear genes; mtDNA mutations; diagnosis; prognosis; biomarker;

   Sammanfattning : Background:Earlier clinical detection of cancer may improve survival as well as offer opportunities for less invasive treatment options. This thesis explores whether the mitochondria and its related genes in the nuclear genome can be used as novel methods for the diagnosis and prognosis of cancers. LÄS MER

4. 13. Cholesterol metabolism in breast cancer: Prognostic factors and optimizing treatment

   Författare :Maria Inasu; Bröstcancer - prevention & intervention; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Statins; Cholesterol; menopausal status; endocrine treatment; disease recurrence;

   Sammanfattning : AbstractBreast cancer (BC) is the most common cancer among women in Sweden and worldwide. Adjuvant endocrine therapies are effective, yet 20-30% patients experience disease relapse. Altered cholesterol metabolism is an emerging hallmark of breast cancer proliferation and endocrine therapy resistance. LÄS MER

5. 14. Metastatic Breast Cancer: Biomolecular Characterization and Targeted Therapy

   Författare :Siker Kimbung; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Metastatic breast cancer; biomarker conversion; liver metastasis-selective genes; prognosis; BRCA1; PARP1;

   Sammanfattning : Metastasis is a complex process that remains a major challenge in the clinical management of cancer, because most cancer-related deaths are attributed to disseminated disease rather than the primary tumor. Despite the significant advances in the prediction of prognosis, and therapeutic management of primary breast cancers, coupled with the substantial improvement in our understanding of the molecular determinants of metastasis, breast cancer relapse and death rates remain unacceptably high. LÄS MER

7. 15. Long-term side effects after treatment of Hodgkin's lymphoma

   Författare :Anne Andersson; Beatrice Melin; Ulf Näslund; Gunilla Enblad; Harald Holte; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hodgkin; survivorship; long-term side effects; cardiovascular disease; second malignancy; infections; prevention; Oncology; Onkologi; onkologi; Oncology;

   Sammanfattning : Background Long-term side effects associated with the treatment of Hodgkin’s lymphoma (HL) have frequently been reported during the last decades. Studies have shown increased mortality in HL survivors. LÄS MER