Sökning: "Cancer of unknown primary"
Visar resultat 1 - 5 av 63 avhandlingar innehållade orden Cancer of unknown primary.
1. Computational exploration of cancer genomes
Sammanfattning : Cancer evolves due to changes in DNA that give a cell an advantage at the expense of the remaining organism. These alterations range from individual base substitutions to broad losses or duplications of chromosomal material. LÄS MER
2. Aspects of Progression in Breast Carcinoma : from ductal carcinoma in situ to invasive cancer
Sammanfattning : In the past decades our knowledge concerning breast cancer progression from ductal carcinoma in situ (DCIS) to invasive cancer has grown rapidly. However, molecular factors driving the progression are still largely unknown. LÄS MER
3. Cellular Effects of Cystatins
Sammanfattning : The exact cellular functions of cystatins are still unknown, and the molecular mechanism leading to their internalization into cells is not yet fully understood. Commonly the cystatins are known to inhibit human lysosomal cysteine proteases (cysteine cathepsins) and it is supposed that this is their primary physiological role. LÄS MER
4. Mechanisms for immune escape in epithelial ovarian cancer
Sammanfattning : Tumors develop mechanisms to subvert the immune system, constituting immune escape. Epithelial ovarian cancer (EOC), the deadliest of all gynecological malignancies, uses a variety of mechanisms to undermine immune surveillance, aiding its establishment and metastatic spreading. LÄS MER
5. Platelets – Multifaceted players in tumor progression and vascular function
Sammanfattning : Platelets play a crucial role for blood hemostasis, the process that prevents bleeding. In addition, platelets have been demonstrated to promote cancer progression and cancer related complications like metastasis and thrombosis. LÄS MER