Sökning: "Calprotectin"

Visar resultat 1 - 5 av 26 avhandlingar innehållade ordet Calprotectin.

1. 1. Faecal Calprotectin Diagnostics : Focus on Primary Care and Suspected Sources of Error

   Författare :Zlatica Rendek; Henrik Hjortswang; Magnus Falk; Ewa Grodzinsky; Stergios Kechagias; Mikael Lilja; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Calprotectin; Inflammatory bowel disease; Gastrointestinal disease; Primary health care; Non-steroidal anti-inflammatory agents; Proton pump inhibitors; Respiratory tract infection;

   Sammanfattning : Patients with gastrointestinal symptoms often present a diagnostic challenge for general practitioners. Faecal calprotectin (FC) is commonly used as a marker of intestinal inflammation and is useful for differentiating between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), as well as for the follow-up of patients with IBD and monitoring treatment response. LÄS MER

3. 2. Chrohn's disease : aspects of epidemiology, clinical course, and faecal calprotectin

   Författare :Yaroslava Zhulina; Jonas Halfvarson; Curt Tysk; Hans Strid; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Crohn’s disease; epidemiology; faecal calprotectin; Medicine; Medicin;

   Sammanfattning : The overall aim of this thesis was to study epidemiological and clinical changes in the natural history of Crohn’s disease, its phenotype, the need for surgery and pharmacological therapy over time, as well as the role of faecal calprotectin as a biomarker of pathophysiology and disease course.An increased incidence and prevalence of Crohn’s disease was seen in the period 1963-2010. LÄS MER

4. 3. Remodelling of extracellular matrix in rectal cancer and preoperative radiotherapy

   Författare :Eva Angenete; Göteborgs universitet; []
   Nyckelord :radiotherapy; rectal cancer; extracellular matrix; MMP-2; PAI-1; uPA; Calprotectin; TGF-beta1;

   Sammanfattning : BACKGROUND Preoperative radiotherapy reduces local recurrence due to rectal cancer, but increases postoperative morbidity. The aim of this thesis was to study the impact of radiotherapy on extracellular matrix (ECM) remodelling enzymes and growth factors after radiotherapy and also their possible use as surrogate markers for complications. LÄS MER

5. 4. Experimental septic shock – Effects of endotoxemia with special reference to pathophysiological responses in the pig

   Författare :Ewa Söderberg; Miklós Lipcsey; Mats B Eriksson; Anders Larsson; Jan Sjölin; Sten Lindahl; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endotoxin; inflammatory response; animal model; timing; steroid treatment; NGAL; Calprotectin; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

   Sammanfattning : Sepsis and septic shock are conditions, with severe outcome or in many cases death. Sepsis is a systemic inflammatory response trigger by bacteraemia but systemic inflammatory response can also be triggered by major trauma, major surgery, pancreatitis, severe burns etc. LÄS MER

7. 5. Systemic sclerosis. Novel molecular and epidemiological features of disease

   Författare :Kristofer Andréasson; Reumatologi och molekylär skelettbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic sclerosis; fibrosis; COMP; calprotectin; biomarker; gastrointestinal;

   Sammanfattning : Systemic sclerosis (SSc) is a systemic rheumatic disease with significant mortality and morbidity. Different estimations of disease prevalence and incidence have been presented from various parts of the world. LÄS MER