Sökning: "Calcium-Binding Protein"

Visar resultat 1 - 5 av 53 avhandlingar innehållade orden Calcium-Binding Protein.

1. 1. Studies of calcium binding proteins 1 and 2 and protein kinase CK2

   Författare :Inger Janson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; calcium binding protein 1; calcium binding protein 2; calcium binding protein 4; erd2receptor; protein kinase CK2; endoplasmic reticulum; Golgi; microsomes; heparin; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

   Sammanfattning : The endoplasmic reticulum (ER) is a major intracellular compartment of eukaryotic cells and is the site of the synthesis and post-translational modification of both secretory and membrane glycoproteins. Upon cell rupture vesicles of several kinds are formed from cell membranes, mainly derived from ER and are called microsomes. LÄS MER

3. 2. Protein Interactions: Electrostatics and Ligand Binding

   Författare :Ingemar André; Biofysikalisk kemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biophysics; Molekylär biofysik; secondary structure formation; protein GB1; pKa values; pH stability; NMR; electrostatic interactions; M proteins; calbindin D9k; calcium binding; cooperativity; calmodulin; calbindin D28k;

   Sammanfattning : This thesis deals with Ca2+ binding to proteins, electrostatic interactions in and between proteins as well as inter- and intramolecular interactions. A computer program was developed to determine Ca2+ binding constants from experimental titration data of proteins. LÄS MER

4. 3. The effect of sequence truncation and amino-acid substitutions on the biophysical properties of protein S and calbindin D9k

   Författare :Karin Julenius; Biofysikalisk kemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; surface plasmon resonance; fluorescence spectroscopy; circular dichroism spectroscopy; NMR spectroscopy; hydrophobic effect; protein stability; dimerization; cooperativity; calcium binding; EGF-module; EF-hand; calbindin D9k; protein S; synthet; Physical chemistry; Fysikalisk kemi;

   Sammanfattning : Protein S is a modular protein and a cofactor in the protein C anticoagulant system. It consists of a Gla-module, a thrombin-sensitive loop, four EGF-modules and a SHBG-like module. LÄS MER

5. 4. The EGF-like Modules of Anticoagulant Protein S. Studies of Ca2+ binding and module interactions

   Författare :Yvonne Stenberg; Malmö Klinisk kemi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; enzymology; Proteins; Klinisk kemi; Clinical chemistry; calcium binding; Protein S; EGF-like module; Proteiner; enzymologi;

   Sammanfattning : Protein S functions as a cofactor to activated protein C (APC) in the degradation of factors Va and VIIIa. In plasma protein S circulates in two forms; 30-40 % circulates as free protein S molecules while the remaining 60-70 % exists in a 1:1 complex with C4b-binding protein (C4BP). Only the free form of protein S functions as a cofactor to APC. LÄS MER

7. 5. Plant Calreticulins -Calcium-binding proteins with many functions

   Författare :Anna Christensen; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; tobacco; plant; calreticulin; isoforms; Arabidopsis; localization; mouse embryonic fibroblasts;

   Sammanfattning : Endoplasmic reticulum (ER) plays an important role in protein synthesis, folding, maturation and transport of newly synthesized proteins, as well as the regulation of cellular Ca2+ homeostasis. A protein that is involved in several of these functions in the ER is calreticulin (CRT), which is a Ca2+-binding chaperone that resides in the lumen of the ER. LÄS MER