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1. 1. Premixed Acidic Calcium Phosphate Cements

   Författare :Jonas Åberg; Håkan Engqvist; Helena Brisby; Peter Thomsen; Marc Bohner; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; monetite; brushite; bone void filler; injecatilbity; in vivo; in vitro;

   Sammanfattning : Calcium phosphate cements are used in medicine to fill bone defects or give support to screws and plates in fracture fixation. The cements are formed via mixing a powder with water and the mixture harden through a dissolution-precipitation reaction. LÄS MER

3. 2. Can Bone Void Fillers Carry Load? : Behaviour of Calcium Phosphate Cements Under Different Loading Scenarios

   Författare :Ingrid Ajaxon; Cecilia Persson; Caroline Öhman-Mägi; Uwe Gbureck; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Calcium phosphate; bone cement; brushite; apatite; monetite; porosity; solvent exchange; degradation; compressive strength; diametral tensile strength; flexural strength; elastic modulus; Poisson’s ratio; fatigue; Teknisk fysik med inriktning mot materialvetenskap; Engineering Science with specialization in Materials Science;

   Sammanfattning : Calcium phosphate cements (CPCs) are used as bone void fillers and as complements to hardware in fracture fixation. The aim of this thesis was to investigate the possibilities and limitations of the CPCs’ mechanical properties, and find out if these ceramic bone cements can carry application-specific loads, alone or as part of a construct. LÄS MER

4. 3. Additives Increasing the Bone-Forming Potential around Calcium Phosphate Cements : Statin, Strontium and Silicon

   Författare :Maryam Montazerolghaem; Marjam Karlsson Ott; Håkan Engqvist; Pedro Granja; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Calcium Phosphate Cements; Osteoblast; Osteoclast; Monetite; Zebrafish; Simvastatin; Strontium; Silicon; Teknisk fysik med inriktning mot materialvetenskap; Engineering Science with specialization in Materials Science;

   Sammanfattning : More than one million people worldwide receive some kind of bone graft each year. Grafts are often needed following bone tumour removal or traumatic fractures to fill voids in the bone and to aid in the healing process. LÄS MER

5. 4. Calcium Phosphate Based Biomaterials for Bone Augmentation

   Författare :Jun Luo; Cecilia Persson; Håkan Engqvist; Marc Bohner; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; bone substitute materials; calcium phosphate cements; apatite; brushite; monetite; setting mechanism; premixed; fibre reinforcement; composite; silk fibroin; mechanical properties; Teknisk fysik med inriktning mot materialvetenskap; Engineering Science with specialization in Materials Science;

   Sammanfattning : Basic (apatite-based) calcium phosphate cements (CPCs), and acidic (brushite and monetite-based) CPCs are used as bone replacement materials because of their bioactivity, mouldability and ability to harden in place. However, their application is limited by their inherent brittleness and difficulties related to their handling. LÄS MER

7. 5. Physical Properties of Acidic Calcium Phosphate Cements

   Författare :Johanna Unosson; Håkan Engqvist; Cecilia Persson; Uwe Gbureck; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

   Sammanfattning : The gold standard for bone replacement today, autologous bone, suffers from several disadvantages, such as the increased risk of infection due to the need for two surgeries. Degradable synthetic materials with properties similar to bone, such as calcium phosphate cements, are a promising alternative. LÄS MER