Sökning: "Calcineurin"

Visar resultat 16 - 20 av 27 avhandlingar innehållade ordet Calcineurin.

  1. 16. NFAT signaling in chronic and acute inflammation - A novel target for the treatment of diabetic vascular complications and acute pancreatitis?

    Detta är en avhandling från Vascular ET-coupling, Lund University

    Författare :Anna Zetterqvist; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NFAT; vascular; diabetes; inflammation; atherosclerosis; diabetic retinopathy; acute pancreatitis; osteopontin; VCAM-1; A-285222;

    Sammanfattning : Diabetic patients suffer from macro- and microvascular complications causing increased morbidity and mortality. How hyperglycemia provokes vascular damage remains unclear, but glucose is believed to fuel a harmful low-grade chronic inflammation of the vessel wall. LÄS MER

  2. 17. Heterobasidion root rot

    Detta är en avhandling från Vascular ET-coupling, Lund University

    Författare :Kerstin Dalman; Sveriges lantbruksuniversitet.; [2010]
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Heterobasidion annosum (Fr.) Bref. sensu lato (s.l. LÄS MER

  3. 18. Effects and mechanisms of actions of cyclosporin, FK506 and 15-deoxyspergualin

    Detta är en avhandling från Stockholm : Karolinska Institutet, false

    Författare :Anette Johansson Borg; Karolinska Institutet.; Karolinska Institutet.; [1995]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cyclosporin; FK506; 15-deoxyspergualin; immunosuppressive effects; transplantation;

    Sammanfattning : Immunosuppressive drugs can be used to deal with unwanted or inappropriateimmune reactions, such as the rejection of a transplanted organ. However, treatmentwith these drugs are often associated with serious adverse effects, and therefore lesstoxic immunosuppressants are desired. LÄS MER

  4. 19. Effects of immunosuppressive drugs on human adipose tissue metabolism

    Detta är en avhandling från Stockholm : Karolinska Institutet, false

    Författare :Maria J Pereira; Göteborgs universitet.; Gothenburg University.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cyclosporin A; tacrolimus; rapamycin; glucocorticoids; new onset diabetes after transplantation; adipocytes; insulin signalling; glucose uptake; lipolysis; lipogenesis;

    Sammanfattning : The immunosuppressive agents (IAs) rapamycin, cyclosporin A and tacrolimus, as well as glucocorticoids are used to prevent rejection of transplanted organs and to treat autoimmune disorders. Despite their desired action on the immune system, these agents have serious long-term metabolic side-effects, including dyslipidemia and new onset diabetes mellitus after transplantation. LÄS MER

  5. 20. Mechanisms of apoptosis in secretory and neuronal cells : role of oxidative stress and calcium overload

    Detta är en avhandling från Stockholm : Karolinska Institutet, false

    Författare :Maria Ankarcrona; Karolinska Institutet.; Karolinska Institutet.; [1996]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Apoptosis is a widespread physiological mechanism to regulate tissue homeostasis bothduring development and in adult organs. However, the cell deletion program can beinappropriately activated or suppressed under pathological conditions. LÄS MER