Sökning: "CSF-1"

Hittade 5 avhandlingar innehållade ordet CSF-1.

  1. 1. Dissection of immunity controlling spread and growth of Listeria monocytogenes in neuronal cells

    Författare :Yuxuan Jin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :L. monocytogenes; nervous system; neuroinvasion; IFN-ã; CSF-1; neuron; NK cells; T cells; MHC;

    Sammanfattning : Listeria monocytogenes is a Grain-positive, facultative intracellular bacterium that causes severe infections in the nervous system of domestic animals and humans. Rhombencephalitis (brainstem encephalitis) due to L. monocytogenes, is a localized brainstem infection that is frequent in ruminants, and has been reported in humans as well. LÄS MER

  2. 2. Studies on myeloid cell functions in periodontitis

    Författare :Reuben Clark; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Periodontitis (PD) is a chronic inflammatory disease characterized by destruction of the tooth supporting tissues; gingiva, periodontal ligament, and alveolar bone. Myeloid cells, including monocytes and macrophages, play a crucial part in the inflammatory host response by clearing pathogens and producing a vast array of inflammatory mediators. LÄS MER

  3. 3. Chemotactic factors in the human follicle at ovulation

    Författare :Eva Runesson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chemokine; follicle; gonadotropin; human; ovary; ovulation;

    Sammanfattning : Ovulation is initiated by the midcycle gonadotropin surge, which leads to a controlled degradation of the follicle wall ending in follicular rupture and oocyte extrusion. The gonadotropins triggers several biochemical and biophysical changes such as vascular alterations, increased proteolytic enzyme activity and leukocyte extravasation, within the preovulatory follicle. LÄS MER

  4. 4. Microglia : health promoting pathways and therapeutic targets in ageing and neuroinflammation

    Författare :Rasmus Berglund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Microglia are the innate immune cells of the CNS with an embryonic origin and self-renew with a slow turnover throughout life. The health-promoting capacities of this cell are being acknowledged through updated and specific tools separating microglia from bone marrow-derived macrophages. LÄS MER

  5. 5. Gateway to the gut : alterations in saliva in inflammatory bowel disease

    Författare :Mirjam Majster; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Inflammatory bowel disease (IBD), which consists of Crohn’s disease and ulcerative colitis, is a chronic immune-mediated disease thought to result from genetic and environmental interaction which influence the commensal flora to trigger an inappropriate mucosal immune response. IBD primarily affects the intestines but is not restricted to them. LÄS MER