Sökning: "CR1"
Visar resultat 1 - 5 av 25 avhandlingar innehållade ordet CR1.
1. Language Constructs for Safe Parallel Programming on Multi-Cores
Sammanfattning : The last decade has seen the transition from single-core processors to multi-cores and many-cores. This move has by and large shifted the responsibility from chip manufacturers to programmers to keep up with ever-increasing expectations on performance. LÄS MER
2. Feedback Enhancement of Antibody Responses via Complement and Fc Receptors
Sammanfattning : IgG, IgM and IgE in complex with antigen have the capacity to regulate specific immune responses. In this investigation, the role of Fc receptors for IgG (FcγRI, FcγRII and FcγRIII) and complement receptors 1 and 2 (CR1/2) for antibody-mediated enhancement of antibody responses are investigated. LÄS MER
3. The Role of IgM and Complement in Antibody Responses
Sammanfattning : An intact complement system including the complement receptors 1 and 2 (CR1/2) is crucial for the generation of a normal antibody response in animals and humans. Moreover, activation of the classical pathway is thought to be important since deficiency in complement components C1q, C2, C4 or C3 lead to impaired antibody responses. LÄS MER
4. IgM and Complement in Regulation of Antibody Responses
Sammanfattning : Animals deficient in complement components C1q, C4, C3, and CR1/2 have severely impaired antibody responses. C1q is primarily activated by antibody-antigen complexes. Antigen-specific IgM in complex with an antigen is able to enhance the antibody response against that antigen. This is dependent on the ability of IgM to activate complement. LÄS MER
5. B cells in Autoimmunity : Studies of Complement Receptor 1 & 2 and FcγRIIb in Autoimmune Arthritis
Sammanfattning : B cells are normally regulated to prevent activation against self-proteins through tolerance mechanisms. However, occasionally there is a break in tolerance and B cells can become self-reactive, which might lead to the development of autoimmune disease. LÄS MER
