Sökning: "CPT-1"

Hittade 1 avhandling innehållade ordet CPT-1.

1. 1. Protein phosphorylation cascades regulating islet beta-cell insulin exocytosis through glucose sensing and drug signaling : with special focus on serine/threonine protein phosphates and hypoglycemic sulfonylureas

   Författare :Mikael Lehtihet; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Diabetes; Islet; Insulin; Exocytosis; Protein phosphatase; Protein kinase; CPT-1; Sulfonylurea; Glutamate; Polyphosphoinositide;

   Sammanfattning : In human type 2 diabetes, loss of glucose-sensitive insulin secretion from the pancreatic �-cell is an early pathogenetic event. Initially, this may be compensated for by stimulating insulin secretion by sulfonylurea drugs. LÄS MER