Sökning: "CPE"

Visar resultat 1 - 5 av 14 avhandlingar innehållade ordet CPE.

  1. 1. The role of wastewater in surveillance and emergence of antibiotic resistant bacteria

    Författare :Marion Hutinel; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Bacteriology; Antibiotic resistance; Surveillance; Horizontal gene transfer; HGT; Conjugation; Plasmids; Epidemiology; CPE; E. coli; Carbapenamase; Linezolid; Colistin; Selection; sul4; OXA-48; gar; NDM; mcr; wastewater; sewage; sewer;

    Sammanfattning : As antibiotic resistance spreads among bacterial pathogens, it reduces treatment options and increases treatment failures of infectious diseases. Strategies employed to reduce this spread or adapt to its consequences need to be based on reliable surveillance data which is lacking in many countries, often due to limited resources. LÄS MER

  3. 2. Molecular Mechanisms Underlying Abnormal Placentation in the Mouse

    Författare :Yang Yu; Reinald H. Fundele; Rolf Ohlsson; J. GRAHAM BURTON; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; IUGR; Placental phenotype; Placental hyperplasia; Diabetes; IHPD; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : Placental development can be disturbed by various factors, such as mutation of specific genes or maternal diabetes. Our previous work on interspecies hybrid placental dysplasia (IHPD) and two additional models of placental hyperplasia, cloned mice and Esx1 mutants, showed that many genes are deregulated in placental dysplasia. LÄS MER

  4. 3. New Functions for Old Genes in the Mouse Placenta

    Författare :Umashankar Singh; Reinald Fundele; Anne C Ferguson-Smith; Uppsala universitet; []
    Nyckelord :Developmental biology; hybrid dysgenesis effects; placental hyperplasia; functional screening; giant cell; glycogen cell; Utvecklingsbiologi;

    Sammanfattning : Different species are separated by pre-zygotic reproductive barriers which impede gene flow between them. Rarely, when pre-zygotic barriers break down, interspecific hybrids are produced that display abnormal phenotypes, collectively called hybrid dysgenesis effects. LÄS MER

  5. 4. Biological Sensing and DNA Templated Electronics Using Conjugated Polymers

    Författare :Per Björk; Olle Inganäs; Wolfgang Fritzsche; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; conjugated polymer; conjugated polyelectrolyte; DNA; sensor; nanowire; Bioengineering; Bioteknik;

    Sammanfattning : Conjugated polymers have been found useful in a wide range of applications such as solar cells, sensor elements and printed electronics, due to their optical and electronic properties. Functionalization with charged side chains has enabled water solubility, resulting in an enhanced interaction with biomolecules. LÄS MER

  7. 5. Glucosyltransferase toxins from clostridia : molecular interactions with cells

    Författare :Esteban Chaves Olarte; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : An enzymatic activity was recently described for the group of Large Clostridial Cytotoxins (LCTs). This activity is glucosyltransfer and consists in the covalent addition of glucose, from UDP-glucose (UDP-Glc) to threonine 35 of small GTPases of the Rho subfamily. LÄS MER