Sökning: "COMT"

Visar resultat 1 - 5 av 28 avhandlingar innehållade ordet COMT.

  1. 1. The Role of Dopamine-Metabolising Enzymes in Renal Sodium Handling. An Experimental Study in vivo

    Författare :Cecilia Odlind; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; dopamine; kidney; sodium; MAO; COMT; rat; mice; RBF; oxygen; renal; L-dopa; DOPAC; entacapone; phenelzine; dopamine receptors; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Sammanfattning : Dopamine (DA) has been shown to act as an intrarenal natriuretic hormone and defects in the renal DA system have been associated with some forms of hypertension. How the DA activity is upregulated durin- increased sodium intake is, however, unknown. LÄS MER

  2. 2. Subjective well-being in old age and its association with biochemical and genetic biomarkers and with physical activity

    Författare :Lovisa A. Olsson; Torbjörn Nilsson; Jan Karlsson; Pär Wändell; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Subjective well-being; Physical activity; Biomarker; Cystatin C; COMT; Cognition; Old age; Geriatrik; Geriatrics;

    Sammanfattning : .... LÄS MER

  3. 3. On the association between panic disorder and autonomic regulation – With special focus on the roles of respiration and on the catechol-O-methyltransferase gene

    Författare :Kristina Annerbrink; Göteborgs universitet; []
    Nyckelord :panic disorder; serotonin; respiration; polymorphism; COMT Val158Met; HCRTR2 G1246A; blood pressure; anthropometry;

    Sammanfattning : Background and aims: Panic disorder is a psychiatric disorder characterized by sudden attacks of intense anxiety. It displays a lot of features suggesting that it may be associated with an underlying aberration in the autonomic regulation of heart activity and respiration: i) the attacks are often characterized by respiratory symptoms and symptoms from the heart, ii) the attacks can be elicited by respiratory stimulants, iii) between attacks, patients with panic disorder often display enhanced respiratory variability and reduced heart rate variability, and iv) patients with panic disorder display enhanced prevalence of respiratory disorders and enhanced mortality in cardiovascular disease. LÄS MER

  4. 4. COMT Genotype, sex steroids, and bone phenotype in mice and men

    Författare :Anna-Lena Eriksson; Göteborgs universitet; []
    Nyckelord :estrogens; SNP; bone; fracture; growth;

    Sammanfattning : COMT GENOTYPE, SEX STEROIDS AND BONE PHENOTYPE IN MAN AND MICE Anna-Lena Eriksson Institute of Medicine, University of Gothenburg, Göteborg, Sweden, 2008 ABSTRACT Sex steroids are of profound importance for several physiological processes including reproduction, growth, and maintenance of skeletal integrity. Serum levels of sex steroids are associated with bone mineral density (BMD) and have been shown to be predictive of fracture risk in older people. LÄS MER

  5. 5. The emotional motor system and gastrointestinal symptoms

    Författare :Pontus Karling; Lars Agréus; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anxiety; ANS; autonomic nervous system; cortisol; DST; emotional motor system; functional; gastrointestinal symptoms; GSRS-IBS; gut; HADS; heart rate variability; HPA axis; IBS; irritable bowel syndrome; stress; unipolar depression; val158met COMT polymorphism; Gastroenterology; Gastroenterologi;

    Sammanfattning : There is a significant comorbidity between anxiety/depression and functional gastrointestinal syndromes, such as irritable bowel syndrome (IBS) and functional dyspepsia. The pathophysiological link between emotions and the gut is not known. LÄS MER