Sökning: "COMT Val158Met"

Hittade 4 avhandlingar innehållade orden COMT Val158Met.

  1. 1. On the association between panic disorder and autonomic regulation – With special focus on the roles of respiration and on the catechol-O-methyltransferase gene

    Författare :Kristina Annerbrink; Göteborgs universitet; []
    Nyckelord :panic disorder; serotonin; respiration; polymorphism; COMT Val158Met; HCRTR2 G1246A; blood pressure; anthropometry;

    Sammanfattning : Background and aims: Panic disorder is a psychiatric disorder characterized by sudden attacks of intense anxiety. It displays a lot of features suggesting that it may be associated with an underlying aberration in the autonomic regulation of heart activity and respiration: i) the attacks are often characterized by respiratory symptoms and symptoms from the heart, ii) the attacks can be elicited by respiratory stimulants, iii) between attacks, patients with panic disorder often display enhanced respiratory variability and reduced heart rate variability, and iv) patients with panic disorder display enhanced prevalence of respiratory disorders and enhanced mortality in cardiovascular disease. LÄS MER

  3. 2. The emotional motor system and gastrointestinal symptoms

    Författare :Pontus Karling; Lars Agréus; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anxiety; ANS; autonomic nervous system; cortisol; DST; emotional motor system; functional; gastrointestinal symptoms; GSRS-IBS; gut; HADS; heart rate variability; HPA axis; IBS; irritable bowel syndrome; stress; unipolar depression; val158met COMT polymorphism; Gastroenterology; Gastroenterologi;

    Sammanfattning : There is a significant comorbidity between anxiety/depression and functional gastrointestinal syndromes, such as irritable bowel syndrome (IBS) and functional dyspepsia. The pathophysiological link between emotions and the gut is not known. LÄS MER

  4. 3. Depression and cardiovascular diseases

    Författare :Aysha Almas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background and aim: The concept of depression as a risk factor for cardiovascular diseases (CVD) is now well known. However, weather the severity of depression has a dose response effect on risk of CVD is not known. LÄS MER

  5. 4. The relation among aging, dopamine-regulating genes, and neurocognition

    Författare :Xin Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : When people are getting old, they often feel increasingly harder to concentrate, and become slower and more inflexible during tasks that involve focused attention, information maintenance in the face of distractions, and when fast switching according to changing goals is required. These cognitive functions are collectively referred to as working memory (WM). LÄS MER