Sökning: "COA"

Visar resultat 1 - 5 av 105 avhandlingar innehållade ordet COA.

  1. 1. Acyl-CoA thioesterases : a component of the peroxisome- proliferator regulated lipid metabolizing system

    Detta är en avhandling från Stockholm : Stockholm University

    Författare :Thomas Svensson; [1995]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lipids; chemistry; metabolism; Thiolester hydrolases; Näringsfysiologi; Ämnesomsättning;

    Sammanfattning : .... LÄS MER

  2. 2. Engineering cytosolic acetyl-CoA metabolism in Saccharomyces cerevisiae

    Detta är en avhandling från Stockholm : Stockholm University

    Författare :Yiming Zhang; [2015]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; reverse engineering; flavodoxin; genomic DNA sequencing; ferredoxin; histone deacetylase; adaptive evolution; ferredoxin flavodoxin NADP reductase; pyruvate decarboxylase; citrate synthase; hexose transporter; yeast; mitochondria; aerobic growth; metabolic engineering.; acetyl-CoA; central carbon metabolism;

    Sammanfattning : A Saccharomyces cerevisiae strain carrying deletions in all three pyruvate decarboxylase genes (also called Pdc negative yeast) represents a non-ethanol producing platform strain for biochemical production. However, it cannot grow on glucose as the sole carbon source due to the lack of cytosolic acetyl-CoA for lipid biosynthesis. LÄS MER

  3. 3. Streptococcus pneumoniae epidemiological, clinical and serological studies

    Detta är en avhandling från Stockholm : Stockholm University

    Författare :Lars Å. Burman; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococcus pneumoniae; incidence; predisposing factors; prognosis; serotyping; etiology of pneumonia; diagnostic methods; COA; CIE; pneumococcal serology;

    Sammanfattning : A retrospective study of invasive pneumococcal disease in patients from Greater Göteborg in 1964- 1980 identified 125 cases of meningitis, 305 of pneumonia, 61 of septicemia with unknown focus, and 17 with other manifestations, all verified by cultures from normally sterile body fluids. The incidence was several times higher in infants and in the elderly than in any other age-group. LÄS MER

  4. 4. Enzymes in the Mycobacterium tuberculosis MEP and CoA Pathways Targeted for Structure-Based Drug Design

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Christofer Björkelid; T. Alwyn Jones; Torsten Unge; Sherry L. Mowbray; William N. Hunter; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Tuberculosis; Mycobacterium tuberculosis; MEP pathway; CoA pathway; drug development; crystal structure; DXR; IspD; PanK; Biokemi; Biochemistry; Molecular Biology; Molekylärbiologi;

    Sammanfattning : Tuberculosis, caused by the pathogenic bacteria Mycobacterium tuberculosis, is one of the most widespread and deadly infectious diseases today. Treatment of tuberculosis relies on antibiotics that were developed more than 50 years ago. These are now becoming ineffective due to the emergence of antibiotic resistant strains of the bacteria. LÄS MER

  5. 5. Fatty Acid Desaturase Activities in Metabolic Syndrome and Cardiovascular Disease Special Reference to Stearoyl-CoA-Desaturase and Biomarkers of Dietary Fat

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Eva Warensjö; Uppsala universitet.; [2007]
    Nyckelord :Nutrition; Fatty acids; Dietary fat; Biomarker; Metabolic Syndrome; Mortality; Obesity; Insulin Sensitivity; Epidemiology; Estimated desaturase activities; Stearoyl-CoA-desaturase; delta-6-desaturase; delta-5-desaturase; Single Nucleotide Polymorphism; Dietary Intervention; Rapeseed oil; Saturated fat; SCD1; Näringslära;

    Sammanfattning : The development of the metabolic syndrome (MetS) and cardiovascular diseases have been suggested to be influenced more by the quality than the amount of dietary fat. The FA composition of serum lipids may be used as biomarkers of dietary fat quality. LÄS MER