Sökning: "CNS tumour"

Visar resultat 1 - 5 av 21 avhandlingar innehållade orden CNS tumour.

  1. 1. Molecular and epigenetic control of CNS tumour and progenitor cells

    Författare :Aileen Gracias; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Despite advances in diagnosis and treatment, CNS tumours continue to result in high mortality and morbidity. Glioblastoma mutliforme (GBM), the most common primary brain tumour, is a recurrent tumour that despite advances in treatment, continues to demonstrate a median time of survival of 14.6 months. LÄS MER

  3. 2. Medical, cognitive and motor outcome after treatment of pilocytic astrocytoma in the posterior fossa in childhood

    Författare :Ingela Kristiansen; Per Frisk; B Strömberg; Klas Blomgren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Childhood; CNS tumour; pilocytic astrocytoma; posterior fossa; long-term outcome; cognition; language; motor performance; learning difficulties; Pediatrik; Pediatrics;

    Sammanfattning : Introduction: Pilocytic astrocytoma is the most common brain tumour in childhood. The aim of the studies was to investigate late medical, cognitive and motor complications in patients treated in childhood for pilocytic astrocytoma in the posterior fossa. LÄS MER

  4. 3. Glioneuronal tumours in childhood : Clinical picture, long-term outcome and possible new treatments

    Författare :Christoffer Ehrstedt; Gunnar Ahlsten; Bo Strömberg; Ann-Margret Rydell; Anja Smits; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioneuronal tumour; ganglioglioma; dysembryoplastic neuroepithelial tumour; childhood; cognition; psychosocial; HRQoL; outcome; mTOR pathway; somatostatin receptor; Pediatrik; Pediatrics;

    Sammanfattning : Background: Glioneuronal tumours are a subgroup of low-grade tumours of the central nervous system (CNS), often causing epilepsy. Overall survival is excellent, but data regarding long-term seizure outcome and late effects are scarce. LÄS MER

  5. 4. Inflammatory proteins in the CNS-relation to Alzheimer's disease

    Författare :Catharina Lindberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Most neurodegenerative disorders are characterised by an inflammatory process in the brain. Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common form of dementia in the elderly. Activated astrocytes and microglia surrounding the amyloid plaques represent evidence for neuroinflammation in the AD brain. LÄS MER

  7. 5. Biomarkers for CNS metastasis in non-small cell lung cancer (NSCLC)

    Författare :Georgios Tsakonas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Non-small cell lung cancer (NSCLC) comprises more than 75% of lung cancer cases and is usually diagnosed in advanced stages. Lung cancer is the leading cause of cancer death among all solid tumours and the second most common malignancy globally. LÄS MER