Sökning: "CD91"

Hittade 4 avhandlingar innehållade ordet CD91.

  1. 1. Immunological mechanisms in systemic autoimmunity : autoantibodies and chemokines in systemic lupus erythematosus and during treatment with TNF inhibitors in rheumatoid arthritis

    Författare :Catharina Eriksson; Karl-Gösta Sundqvist; Solbritt Rantapää-Dahlqvist; Mari Norgren; Thomas Skogh; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoimmunity; chemokines; T-cells; autoantibodies; CD91; Clinical immunology; Klinisk immunologi; Rheumatology; Reumatologi; Clinical Immunology; klinisk immunologi; reumatologi; rheumatology;

    Sammanfattning : Background. Rheumatoid Arthritis (RA) is an autoimmune inflammatory disease that, without powerful treatment, may lead to irreversible joint damage. During the past decade, anti-cytokine therapy has become available, e.g. LÄS MER

  3. 2. Atom and Group Transfer Reactions Involving High-valent Iron Complexes

    Författare :Yong Li; Kemisk fysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Iron enzymes; high-valent iron intermediates; bio-inspired iron complexes; FeIV=O; FeIV=NR; catalytic reactions; electronic effects; steric restriction.;

    Sammanfattning : Iron enzymes play critical roles in biological oxidation reactions by utilizing highly reactive high-valent iron intermediates, such as FeIV=O, FeV(O)(OH), and FeIV=NR species, for catalytic reactions. These intermediates exhibit remarkable catalytic behavior with high reactivities and high regio- and stereospecificity in various biochemical reactions. LÄS MER

  4. 3. Thrombospondin 1, an autocrine regulator in T cell adhesion and migration

    Författare :ShuShun Li; Karl-Gösta Sundqvist; Jan Holgersson; Claes Dahlgren; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; T cell; adhesion; migration; thrombospondin; Immunologi; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Lymphocytes, the principal cells of the immune system, perform the immune function throughout the body by their unique capacity to circulate in blood stream and lymphatic vessels and migrate in lymphoid and non-lymphoid tissues. The mechanisms regulating lymphocyte adhesion and migration, interactions with cells and components within the extracellular matrix are not fully understood. LÄS MER

  5. 4. Endogenous thrombospondin-1 and proteases in the regulation of lymphocyte adhesion and motility

    Författare :Anna Forslöw; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The human immune system, which protects the body from invading pathogens, largely depends on the proper function of lymphocytes, which are highly motile and constantly recirculate the blood and lymph. Adhesive and motile capability is often amplified or uncontrolled during chronic inflammatory conditions such as autoimmune diseases. LÄS MER