Sökning: "CD8"

Visar resultat 16 - 20 av 411 avhandlingar innehållade ordet CD8.

  1. 16. Dissection of the tonsillar cancer immune microenvironment : Perspectives of the myeloid APC – T-cell axis

    Författare :David Gomez Jimenez; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dendritic cell; Macrophage; CD8 T-cell; Human papillomavirus HPV ; Tonsillar cancer; Tumor microenvironment; Immuno-oncology; Single-cell RNA sequencing; Spatial proteomics; Flow Cytometry;

    Sammanfattning : Tonsillar cancer (TC) is a subset of head and neck cancer (HNC). TC incidence is sharply rising due to an increased prevalence of human papillomavirus (HPV) infection in the western world. Currently HPV status is considered during clinical staging due to its positive association to patient prognosis. LÄS MER

  3. 17. Cellular Immune Responses to Cytomegalovirus

    Författare :Anna Karin Lidehäll; Olle Korsgren; Thomas Tötterman; Ineke ten Berge; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytomegalovirus; cellular immunology; infection; immune responses; congenital infection; CD4 T cells; CD8 T cells; immunosuppressed; Clinical immunology; Klinisk immunologi;

    Sammanfattning : Cytomegalovirus (CMV) is a widespread infection affecting 50-90% of the human population. A typical silent primary infection is followed by life-long persistence in the host under control by virus-specific CD8 (“killer”) and CD4 (“helper”) T cells. LÄS MER

  4. 18. Herpesvirus Infection and Immunity in Neurocognitive Disorders

    Författare :Gabriel Westman; Britt-Marie Eriksson; Martin Ingelsson; Olle Korsgren; Jan Ernerudh; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; Herpes simplex encephalitis; Herpesvirus; Cytomegalovirus; CMV; HSV-1; HHV-6; CD8 T-cells; Cellular immunity; Immunosenescence; Autoimmunity; NMDA receptor; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Herpesviruses have co-speciated with several vertebrate and invertebrate animals throughout the history of evolution. In the immunocompetent human host, primary infection is usually benign, whereafter the virus is brought into life-long latency. LÄS MER

  5. 19. Requirements for the Induction of Adaptive Immune Responses to Rotavirus

    Författare :Joy Nakawesi; Virusrekognition; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rotavirus; classical dendritic cells; Lymphoid organ hypertrophy; B cells; IgA; Retinoic acid; CD8 T cells; TLR3 and Poly I:C ;

    Sammanfattning : Rotavirus (RV) infections remain the leading cause of world-wide diarrhea-associated morbidity and mortality among children 200,000 deaths annually mostly in the low-income countries of Africa and Asia. Efficient clearance of the primary RV infection and protection from future re-infections is mediated by adaptive immune responses. LÄS MER

  7. 20. Immunity to Rotavirus infection across ages

    Författare :Konjit Getachew Muleta; Virusrekognition; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rotavirus; B cells; T cells; Dendritic cells; Mesenteric Lymph Node; CD8 T cells; Maternal protection; IgA; Neonates; Small Inestinal lamina propria; IFNAR signaling;

    Sammanfattning : Rotavirus (RV) is a double-stranded RNA virus that mainly affects young children under the age of five years. It is one of the leading causes of dehydrating gastroenteritis. Every year, about 200,000 child deaths occur due to RVinfection. Vaccines exist and are in use worldwide. LÄS MER