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Visar resultat 1 - 5 av 411 avhandlingar som matchar ovanstående sökkriterier.

1. 1. The Immune System in the Oldest-Old : Clinical and Immunological Studies in the NONA Immune Cohort

   Författare :Bengt-Olof Nilsson; Jan Ernerudh; Anders Wikby; Sture Löfgren; Karlis Pauksens; Linköpings universitet; []
   Nyckelord :Elderly; selection; health status; lymphocyte subsets; CD8; CMV; cytomegalovirus; immune risk; immune risk phenotype; IRP; T-cells; interleukin 6; IL-6; survival; mortality; antinuclear antibodies; ANA; ageing; immunosenescence; MEDICINE; MEDICIN;

   Sammanfattning : The oldest-old (people aged 80 or older) constituted 5 % of the population in Sweden in 2000, an increase from 1.5 % fifty years earlier. The immune system undergoes dramatic changes at high age, sometimes referred to as “immunosenescence”. LÄS MER

3. 2. The use of immunological biomarkers to improve individualization of postoperative radiotherapy in breast cancer

   Författare :Axel Stenmark Tullberg; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tumor-infiltrating lymphocytes; CD8; FOXP3; Radiotherapy; Breast cancer;

   Sammanfattning : Radiotherapy (RT) forms the cornerstone of most curative breast cancer treatment due to its well-established risk-reducing effect on local recurrences at the population level. However, there is heterogeneity regarding treatment benefits at the individual level, and research currently aims to better tailor treatment decisions based on tumor biology. LÄS MER

4. 3. HIV-1 evolution, disease progression and molecular epidemiology of HIV-1 single and HIV-1 and HIV-2 dual-infected individuals in Guinea-Bissau

   Författare :Joakim Esbjörnsson; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; HIV-2; Guinea-Bissau; subtype; disease progression; evolution; coreceptor tropism; CXCR4; gp120; V1-V3; CD4%; CD8%; soluble immune markers;

   Sammanfattning : The two genetically related human lentiviruses known today, HIV-1 (which is pandemic) and HIV-2 (which mainly is confined to West Africa), are the causative agents of AIDS. Progressive immune dysfunction and AIDS develop in most cases of untreated HIV-1 infection, but only in approximately 25-30% of HIV-2 infected individuals. LÄS MER

5. 4. Tissue transglutaminase autoantibodies in childhood celiac disease

   Författare :Daniel Agardh; Pediatrisk endokrinologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; serologi; Medicine human and vertebrates ; Medicin människa och djur ; Immunology; serology; transplantation; villous atrophy; T cells; serological marker; screening; intestinal mucosa; children; celiac disease; CD25; CD8; CD4; autoantibodies; B cells; gluten-free diet; autoimmunity;

   Sammanfattning : Celiac disease is a prevalent small bowel disease in children caused by permanent intolerance against gliadin, which is the alcohol-soluble fraction of the cereal protein gluten in wheat, rye and barley. Celiac disease is characterized by an inflammatory infiltrate of CD4+ T lymphocytes in the intestinal mucosa leading to damage of villous structure and loss of absorptive surface. LÄS MER

7. 5. Dissecting nasopharyngeal cancer. Studies on prerequisites for antigen-specific active immunotherapy

   Författare :Johan Nilsson; Lund näs- och halssjukdomar Öron-; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nasopharyngeal carcinoma; Epstein-Barr virus; dendritic cells; CD207; CD8; cancer immune phenotypes; nanoparticles;

   Sammanfattning : .... LÄS MER