Sökning: "CD8 T-cells"

Visar resultat 21 - 25 av 318 avhandlingar innehållade orden CD8 T-cells.

1. 21. Potential immunoregulatory role of T and dendritic cells in cancer : Investigations based on transcriptional analysis

   Författare :Milad Abolhalaj; Institutionen för immunteknologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dendritic cells; T cells; head and neck cancer; acute myeloid leukemia; bladder cancer; T cell exhaustion;

   Sammanfattning : Cancer is a complex disease with various genetic and epigenetic driving factors. Cancer cells form a favored microenvironment to sustain their uncontrolled behavior leading to abnormal growth. With standard treatment including chemotherapy, relapse risk is high due to the resistance that cancer cells can develop against chemotherapy agents. LÄS MER

3. 22. T Cell Ontogeny and Effector Functions in Galphai2-deficient Colitis

   Författare :Malin Bjursten; Göteborgs universitet; []
   Nyckelord :colitis; T cells; Galphai2- - mice; thymus; pro-inflammatory cytokines; alpha4 integrin;

   Sammanfattning : Inflammatory bowel disease (IBD) comprising Crohn s disease and ulcerative colitis is a disease that affects millions of people worldwide, especially in northern countries such as Sweden, and is characterised by chronic uncontrolled inflammation of the intestinal mucosa. It is the general belief that multiple factors such as genetic and environmental aspects are involved in disease pathogenesis. LÄS MER

4. 23. Immunological effects of isolated regional perfusion in malignant melanoma

   Författare :Junko Johansson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanoma; Isolated regional perfusion; ILP; IHP; Melphalan; Immunogenic cell death; T cells; Monocytes; ISG;

   Sammanfattning : Malignant melanoma patients with metastatic disease confined to the limbs or liver may be treated with hyperthermic isolated regional perfusion with a chemotherapeutic agent, most commonly melphalan. This procedure enables much higher tissue concentrations of the chemotherapeutic agent compared with systemic administration. LÄS MER

5. 24. Atherosclerotic cardiovascular disease in rheumatoid arthritis : aspects of pathogenesis and risk

   Författare :Bengt Wahlin; Solveig Wållberg-Jonsson; Anna Södergren; Anders Bengtsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; inflammation; atherosclerosis; cardiovascular disease; risk estimation; cytomegalovirus; T-cells; bone turnover; osteoprotegerin; osteocalcin; Medicine; medicin;

   Sammanfattning : Patients with rheumatoid arthritis (RA) have an increased prevalence and severity of atherosclerosis, and a corresponding increased risk of cardiovascular disease. The mechanisms causing this are not well elucidated, but both traditional cardiovascular risk factors and RA-associated factors have been associated with atherosclerosis and increased risk of cardiovascular events in patients with RA. LÄS MER

7. 25. Immunomodulatory properties of steroid hormones

   Författare :Maria Taube; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DTH; oestradiol; corticosteroids; T cells; SCID mice; adoptive transfer; thymus; spleen.;

   Sammanfattning : Recent epidemiological, clinical and experimental evidence have suggested that steroid hormones play an important role in immune responses and in immune-mediated diseases. Many autoimmune diseases are treated with corticosteroids. LÄS MER