Sökning: "CD8 T-cells"

Visar resultat 11 - 15 av 318 avhandlingar innehållade orden CD8 T-cells.

  1. 11. T cells and smoke-induced airway inflammation

    Författare :Mikael Mikko; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic obstructive pulmonary disease (COPD) is an inflammatory disease primarily caused by longterm cigarette smoking. The disease is characterized by both tissue remodelling and an accumulation of inflammatory cells including macrophages, neutrophils and T cells, in the lung. LÄS MER

  3. 12. The Immune System in the Oldest-Old : Clinical and Immunological Studies in the NONA Immune Cohort

    Författare :Bengt-Olof Nilsson; Jan Ernerudh; Anders Wikby; Sture Löfgren; Karlis Pauksens; Linköpings universitet; []
    Nyckelord :Elderly; selection; health status; lymphocyte subsets; CD8; CMV; cytomegalovirus; immune risk; immune risk phenotype; IRP; T-cells; interleukin 6; IL-6; survival; mortality; antinuclear antibodies; ANA; ageing; immunosenescence; MEDICINE; MEDICIN;

    Sammanfattning : The oldest-old (people aged 80 or older) constituted 5 % of the population in Sweden in 2000, an increase from 1.5 % fifty years earlier. The immune system undergoes dramatic changes at high age, sometimes referred to as “immunosenescence”. LÄS MER

  4. 13. Tissue transglutaminase autoantibodies in childhood celiac disease

    Författare :Daniel Agardh; Pediatrisk endokrinologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; serologi; Medicine human and vertebrates ; Medicin människa och djur ; Immunology; serology; transplantation; villous atrophy; T cells; serological marker; screening; intestinal mucosa; children; celiac disease; CD25; CD8; CD4; autoantibodies; B cells; gluten-free diet; autoimmunity;

    Sammanfattning : Celiac disease is a prevalent small bowel disease in children caused by permanent intolerance against gliadin, which is the alcohol-soluble fraction of the cereal protein gluten in wheat, rye and barley. Celiac disease is characterized by an inflammatory infiltrate of CD4+ T lymphocytes in the intestinal mucosa leading to damage of villous structure and loss of absorptive surface. LÄS MER

  5. 14. T cells in chronic obstructive pulmonary disease

    Författare :Ester Roos-Engstrand; Anders Blomberg; Anders Bucht; Annelie F Behndig; Magnus Sköld; Claes-Göran Löfdahl; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; airway epithelium; bronchoscopy; bronchoalveolar lavage; endobronchial mucosal biopsies; inflammation; flow cytometry; T lymphocytes; CD25; CD127; FoxP3; Lung diseases; Lungsjukdomar; lungmedicin; Lung Medicine;

    Sammanfattning : Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but the mechanisms by which cigarette smoke induces COPD are still elusive. T lymphocytes have been implicated in the pathogenesis of the disease, but their role in the airway inflammation in COPD is not fully understood. LÄS MER

  7. 15. Acquisition and function of NK cell-associated molecules on T cells

    Författare :Erika Assarsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Natural killer cells; Natural Killer T cells; T cells; Receptors; Cytokines; Influenza A virus; Activation; Proliferation; Interactions;

    Sammanfattning : One challenge for multicellular organisms, including humans, is to cope with a broad variety of microorganisms and their rapid replication and alterations. To do this, both fast and specific defense mechanisms are needed that can control threatening infections. LÄS MER