Sökning: "CD8 T cell"

Visar resultat 16 - 20 av 342 avhandlingar innehållade orden CD8 T cell.

1. 16. T-cells in COPD to help or harm? A study of T-cells in COPD patients and related aspects of T-cell function in vitro

   Författare :Pernilla Glader; allergologi och palliativ medicin Lungmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Andningsorganen; Respiratory system; Immunologi; serologi; T-cell; inflammation; mucosal immunology; transplantation; serology; Immunology; lymphocyte; chronic obstructive pulmonary disease;

   Sammanfattning : Chronic obstructive pulmonary disease, COPD, is manifested by chronic airflow limitation due to inflammation and tissue destruction in the lungs. COPD is caused primarily by smoking and with increasing cigarette consumption in the world, the prevalence for COPD will most probably increase in the future. LÄS MER

3. 17. Immunomodulatory Effects of Human ImmunodeficiencyVirus (HIV-1) on Dendritic Cell and T cell Responses : Studies of HIV-1 effects on Dendritic cell functionality reflected in primed T cells

   Författare :Karlhans Fru Che; Marie Larsson; Jorma Hinkula; Karl-Eric Magnusson; Douglas Nixon; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The human immunodeficiency virus (HIV)-1 is the causative agent of acquired immune deficiency syndrome (AIDS) worldwide. Till date there are no vaccines or cure for this infection as the virus has adapted myriad ways to remain persistent in the host where it causes severe damage to the immune system. LÄS MER

4. 18. Human intraepithelial lymphocytes : a comparative study of phenotype, morphology, and functional properties of intraepithelial lymphocytes in gut and oral mucosa

   Författare :Carina Lundqvist; Marie-Louise Hammarström; Sten Hammarström; Per Brandtzaeg; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human intraepithelial lymphocytes; alimentary tract; intestinal epithelium; gut luminal antigens; gingiva; γδ T cells; immunoelectron microscopy; cytokine mRNA; RT-PCR; extrathymic T cell maturation; RAG-1; periodontitis; mucosal immune system; CD4-CD8- αβ T cells; CD8 γδ T cells;

   Sammanfattning : Human intraepithelial lymphocytes (IEL) constitute a unique cell population situated in the first line of defense of the alimentary tract. Here they are continuously exposed to a massive antigenic load of high complexity. However, different conditions prevail along the alimentary tract. LÄS MER

5. 19. Extrathymic T cell receptor gene rearrangement in human alimentary tract

   Författare :Anna Bas; Marie-Louise Hammarström; Sten Hammarström; Adrian Hayday; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; T cell maturation; recombination activating gene; preTα; human intestinal mucosa; intraepithelial lymphocytes; lamina propria lymphocytes; nasopharyngeal tonsil; Immunologi; Immunology; Immunologi; immunologi; Immunology;

   Sammanfattning : T lymphocytes regulate the initiation, duration, and magnitude of adaptive immune responses and function as effector cells in cell mediated immunity. To become immunologically competent they must generate functional antigen receptors. This process takes place in the thymus and requires somatic recombination of T cell receptor (TCR) genes. LÄS MER

7. 20. Towards Immunotherapy of Midgut Carcinoid Tumors

   Författare :Sofia Vikman; Thomas Tötterman; Valeria Giandomenico; Bengt Widegren; Uppsala universitet; []
   Nyckelord :Immunology; midgut carcinoid; gene expression; immunotherapy; tumor antigen; VMAT-1; T cell; HLA-A*0201-binding peptide; IFNγ; regulatory T cell; Immunologi;

   Sammanfattning : Classical midgut carcinoids belong to neuroendocrine tumors of the gastroenteropancreatic tract (GEP-NETs) and are associated with serotonin overproduction. The term midgut is derived from the tumors’ embryological site of origin: enterochromaffin cells in the lower jejunum, ileum, caecum and the ascending colon. LÄS MER