Sökning: "CD68"
Visar resultat 11 - 15 av 42 avhandlingar innehållade ordet CD68.
11. Investigation of immune cell-derived factors as potential biomarkers in patients with colorectal cancer
Sammanfattning : Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer related death. It is a heterogeneous disease involving multiple molecular pathways that result in differing phenotypes. Individual variability in CRC susceptibility is influenced by genetic variation, such as single nucleotide polymorphisms (SNPs). LÄS MER
12. Acute pancreatitis, from local defense to remote organ injury
Sammanfattning : Acute pancreatitis (AP) is an inflammatory disease of the pancreas. Acute abdominal pain is the most common symptom. Pancreatic injury is mild in 80% of patients, who recover without complications. The remaining patients have a severe disease with local and systemic complications such as acute lung injury (ALI). LÄS MER
13. Spatial immune analyses in clinical cancer tissue
Sammanfattning : Cancer is a leading cause of premature death and lung cancer is the deadliest cancer type, with non-small cell lung cancer (NSCLC) representing 85% of lung cancer cases. Despite promising development in cancer treatment in recent decades, overall prognosis is poor. LÄS MER
14. On osseointegration in response to controlled surface nanotopography
Sammanfattning : Knowledge about the biological responses provoked by the surface modification of titanium implants on the nanoscale is still in its infancy. Although in vitro studies claim superior effects considering higher adhesion and proliferation of osteoblasts in the short term and even differentiation towards the osteogenic cell lineage in the long term, these responses do not necessarily reflect the actual outcome in the complex in vivo environment. LÄS MER
15. Cellular and molecular mechanisms of inflammatory arthritis and fibromyalgia
Sammanfattning : In Study I, we examined the impact of the hR100E-NGF mutation on inflammatory pain and bone erosion in both female and male mice. Our findings indicate that the hR100E-NGF mutation did not affect the development of the peripheral sensory nervous system at the lumbar DRG, sciatic nerve, ankle joint, or glabrous skin. LÄS MER