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Visar resultat 1 - 5 av 42 avhandlingar som matchar ovanstående sökkriterier.
1. The impact of Wnt5a signaling and tumor associated macrophages in breast cancer
Sammanfattning : Breast cancer is the most common cancer among women worldwide with approximately 1.150.000 new cases each year and accounting for over 400.000 deaths per year. LÄS MER
2. Healing of endosseous implants with different surface characteristics in grafted and non-grafted bone : clinical and experimental studies
Sammanfattning : Aims: This study uses radiological and clinical evaluations of the healing of endosseous titanium implants presented with different surface characteristics in the clinical situation (paper I-III) and experimentally to describe the early bone healing in maxillary sinus membrane elevation with and without the use of grafting material (paper IV).Material and methods: In paper I, 136 patients were treated with 394 dental implants – 199 were oxidized titanium implants (Nobel Biocare TiUnite) and 195 were turned titanium surface implants (Nobel Biocare Mark III). LÄS MER
3. Immunologic Markers in the Tumor Microenvironment of Classical Hodgkin Lymphoma
Sammanfattning : In classical Hodgkin lymphoma (cHL), cytokine regulation and cellular composition of the tumor microenvironment (TME) is crucial for tumor cell survival. In paper I, we examined the presence of CD138+ plasma cells and IgG4+ plasma cells in diagnostic cHL biopsies with immunohistochemistry (IHC). LÄS MER
4. Oral chronic Graft-versus-host disease : clinical and pathological staging
Sammanfattning : Allogenic hematopoietic cell transplantation (HCT) is a curative treatment for many patients with immune- hematopoietic disorders, mainly hematopoietic cancers as leukaemia. Chronic Graft-versus-Host Disease (cGVHD) is a major long-term complication, associated with mortality and morbidity following allogenic HCT. LÄS MER
5. Novel markers for smooth muscle cell modulation in vascular injury and disease
Sammanfattning : Smooth muscle cells (SMCs) are major constituents of the vascular wall, indispensable for basic physiological functions of a healthy vessel, such as regulating vascular tone and blood pressure, but also critical during disease development. With remarkable plasticity, SMCs act as early responders to vessel wall injury, where by activating molecular mechanisms, including phenotypic modulation and transdifferentiation, they counteract detrimental stimuli and aim to restore vascular homeostasis. LÄS MER