Sökning: "CD45"
Visar resultat 1 - 5 av 34 avhandlingar innehållade ordet CD45.
1. Identification and characterization of progenitor populations in the human adult heart
Sammanfattning : Traditionally, the heart has been regarded as a non-regenerative organ. During the last 10 years, this notion has been challenged. By 14C measurements, it was calculated that at the age of 50, about 45% of all cardiomyocytes had formed after birth. LÄS MER
2. Protein Dimensions and Interactions at Immune-Cell Contacts
Sammanfattning : Immune cells, such as B and T cells, fight pathogens infecting the human body. To fulfil this function the immune cells need to form a contact during which different membrane proteins play an important role. LÄS MER
3. Adult Stem Cell Plasticity, Hype or Hope?
Sammanfattning : Several studies have reported that bone marrow (BM)-derived stem cells have the capacity to give rise to cells of different type of tissue; an ability termed stem cell plasticity or transdifferentiation. Controversies exist as to how frequent this phenomenon is, or if it may be explained by alternative mechanisms. LÄS MER
4. Therapeutic response in human cancers : the dual role of STAT signalling
Sammanfattning : STAT proteins were discovered as the mediators of interferon (IFN) signalling in response to viral infections. Later, it has become evident that STATs are activated by many stimuli and that they exert multifaceted effects by regulating gene transcription. LÄS MER
5. MESENCHYMAL STEM- AND STROMAL CELLS IN BONE MARROW AND OSTEOSARCOMA
Sammanfattning : Primary mesenchymal stem cells (MSC) play a central role in bone marrow (BM) and during haematopoiesis. Yet, the exact phenotype and spatial distribution of primary MSC in the human BM are unknown. Their cultured progeny are promising candidates for clinical applications. LÄS MER