Sökning: "CD4 T cells"
Visar resultat 21 - 25 av 497 avhandlingar innehållade orden CD4 T cells.
21. Human intraepithelial lymphocytes : a comparative study of phenotype, morphology, and functional properties of intraepithelial lymphocytes in gut and oral mucosa
Sammanfattning : Human intraepithelial lymphocytes (IEL) constitute a unique cell population situated in the first line of defense of the alimentary tract. Here they are continuously exposed to a massive antigenic load of high complexity. However, different conditions prevail along the alimentary tract. LÄS MER
22. Binding Kinetics of Proteins at Immune-Cell Contacts
Sammanfattning : Protein-protein interactions are crucial in numerous cellular functions and biological processes that take place inside our body. It is therefore not surprising that these interactions also govern the response of our body´s defence mechanism, the so-called immune system, towards an infection. LÄS MER
23. T cells in chronic obstructive pulmonary disease
Sammanfattning : Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but the mechanisms by which cigarette smoke induces COPD are still elusive. T lymphocytes have been implicated in the pathogenesis of the disease, but their role in the airway inflammation in COPD is not fully understood. LÄS MER
24. Regulatory properties of dendritic cells and B cells in adaptive immunity
Sammanfattning : This thesis is based upon four original papers in which human dendritic cells (DCs) and B cells have been analyzed in terms of how they influence the character of adaptive immune responses. DCs isolated from human tonsils were found to possess a capacity to directly regulate proliferation, isotype switching, and antibody production in B cells. LÄS MER
25. CD4+CD25+ T regulatory cells in multiple sclerosis
Sammanfattning : Multiple sclerosis (MS) is a chronic, inflammatory, and demyelinating disease of the central nervous system (CNS), which is likely to be mediated by autoaggressive immunity. Treatments of MS that may beneficially influence the disease course consist of Avonex (interferon-beta; IFN-beta), and Copaxone (glatiramer acetate; GA). LÄS MER