Sökning: "CD4 T cells"

Visar resultat 16 - 20 av 497 avhandlingar innehållade orden CD4 T cells.

1. 16. Innate and adaptive immunity in genital HSV-2 infection: Implications for vaccine development

   Författare :Ali M Harandi; Göteborgs universitet; []
   Nyckelord :genital herpes infection; natural antibody; CD4 T cells; CD8 T cells; IFN-g; IL-12; IL-18; CC chemokines; dendritic cells.;

   Sammanfattning : Herpes simplex virus type 2 (HSV-2) is a sexually transmitted pathogen that infects the genital tract mucosa and is the most common case of genital ulcers in humans. Despite numerous studies, little is known about the mechanisms involved in immune protection and no anti-herpes vaccine has been developed to date. LÄS MER

3. 17. Antibody Feedback Regulation : From Epitope Masking to T Helper Cell Activation

   Författare :Andrew Getahun; Birgitta Heyman; Hans-Gustaf Ljunggren; Daniel Conrad; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immune regulation; B cells; T cells; Antibodies; Fc Receptors; Antigen presentation; Transgenic Knockout Mice; Immunologi; Immunology; Immunologi;

   Sammanfattning : Antibodies have the ability to influence the antibody response against the very antigen they are specific for, in a process called antibody feedback regulation. Depending on the nature of the antigen, the antibody response can be either enhanced or almost completely inhibited. LÄS MER

4. 18. CD25+CD4+ regulatory T cells in rheumatic disease

   Författare :Duojia Cao; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Human; rheumatic disease; synovial fluid; regulatory T cells; FOXP3; suppression; tolerance; autoimmunity;

   Sammanfattning : CD25+CD4+ T cells represent a unique cell lineage of thymus derived naturally occurring regulatory T cells. The gene Foxp3 (mouse)/ FOXP3(human) is strictly related to their generation in the thymus and their regulatory function in the periphery. LÄS MER

5. 19. Immunoregulation in an experimental model of allergic asthma

   Författare :Magnus Korsgren; Avdelningen för klinisk kemi och farmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergic asthma; macrophage migration inhibitory factor; eosinophils; gd T cells; NK1.1 T cells; natural killer cells; immunoglobulins; B cells; innate immunity; allergic airway inflammation; immediate hypersensitivity; Physiology; Fysiologi; Immunology; serology; transplantation; Immunologi; serologi;

   Sammanfattning : In allergic asthma the immune response to antigen is inappropriate, leading to an inflammatory process in the respiratory mucosa. To further elucidate immunological mechanisms involved in the development of such inflammation, control mice and mice deficient in selected cell types or proteins, were used in experimental models of allergic asthma and anaphylaxis. LÄS MER

7. 20. Insulin promotes GABA signalling modulation in both the mouse hippocampus and human CD4+ T cells

   Författare :Hayma Hammoud; Bryndis Birnir; Fredrik Elinder; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gamma-aminobutyric acid; hippocampus; tonic currents; CD4 T cells; glucose; insulin; cytokines; proliferation.; Medical Cell Biology; Medicinsk cellbiologi;

   Sammanfattning : Gamma-aminobutyric acid (GABA) is the most common inhibitory neurotransmitter in the adult mammalian brain, where it mediates several biological functions. Rapid inhibition is predominantly mediated by the activation of GABA-A receptors that are ubiquitously expressed across the central nervous system in a cell-, circuit-, or region-specific manner. LÄS MER