Sökning: "CD3?"
Visar resultat 1 - 5 av 186 avhandlingar innehållade ordet CD3?.
1. Regulatory T cells and mucosal-associated invariant T cells in colon adenocarcinomas; Phenotype and function
Sammanfattning : In many solid cancers, and also in colon adenocarcinomas, an increased accumulation of lymphocytes is beneficial for the patient. However, tumor-infiltrating immune cells may be either pro- or anti-tumorigenic and the balance between these two counteracting forces partly determines patient outcome. LÄS MER
2. Mast cells in Hodgkin lymphoma : or 'What's a nice cell like you doing in a tumour like this?'
Sammanfattning : Mast cell (MC) accumulation around tumours is an old observation gaining new relevance due to the multifaceted nature of MCs and their many roles in immunity, beyond allergy. Knowledge about tumour specific recruitment of, and interactions with, MCs is needed to unravel the function of their presence. LÄS MER
3. Angiogenesis in human renal cell carcinoma : hypoxia, vascularity and prognosis
Sammanfattning : Background: Angiogenesis is recognised as a critical step in tumour progression. The angiogenic switch is activated by various trigger signals, such as hypoxia, low pH, and genetic mutations. Renal cell carcinoma (RCC) is often an aggressive tumour, and advanced disease has limited treatment options and bad prognosis. LÄS MER
4. Exploring the heterogeneity of the hematopoietic stem and progenitor cell pool in cord blood
Sammanfattning : Hematopoietic stem cell transplantation (HSCT) is a curative treatment for a wide range of malignant and hereditary disorders. It is yet the only clinically established stem cell treatment. LÄS MER
5. Functional studies of candidate genes contributing to type 1 diabetes in the NOD mouse
Sammanfattning : Type 1 Diabetes (T1D) is an autoimmune disorder caused by both genetic and environmental factors. The non-obese diabetic (NOD) mouse is one of the best and most commonly studied animal models for T1D. This mouse strain spontaneously develops diabetes through a process that closely resembles the human pathogenesis. LÄS MER