Sökning: "CCR3"
Visar resultat 1 - 5 av 15 avhandlingar innehållade ordet CCR3.
1. Human eosinophils and their activation by allergens via danger signal receptors
Sammanfattning : Human eosinophilic granulocytes are polymorphonuclear cells with a powerful arsenal of cytotoxic substances in their granules, which are mainly found in the gastrointestinal mucosa, and the respiratory and genitourinary tracts. Their physiological role is incompletely understood, although it is likely they protect the mucosal surfaces, perhaps by recognizing danger signals present on microorganisms or released from damaged tissue. LÄS MER
2. Chemokines and bone : lessons from in vitro and in vivo studies
Sammanfattning : Bone homeostasis is maintained by the balanced activity of bone-forming osteoblasts and bone-resorbing osteoclasts. Inflammation in the vicinity of bone disturbs the balanced bone remodeling process, which often results in bone loss. LÄS MER
3. Dynamics of HIV coreceptors and their utilization by plasma and cerebrospinal fluid HIV-1 isolates
Sammanfattning : HIV-1 infection of CD4+ immune cells requires the assistance of cellular coreceptors. The regulation of these receptors is highly dynamic. In addition to the major coreceptors, CCR5 and CXCR4, several alternative coreceptors mediate entry for selected HIV isolates in vitro, although their role in vivo is yet to be established. LÄS MER
4. Novel Insights into Inflammatory Disturbed Bone Remodelling
Sammanfattning : Bone is a dynamic tissue that is continuously remodelled, a process that requires equal amounts of osteoclastic bone resorption and osteoblastic bone formation. Inflammation may disturb the equilibrium and result in local and/or systemic bone loss. Negative bone mass balance occurs in several chronic inflammatory diseases, e.g. LÄS MER
5. Eosinophils, their progenitors and T helper cells in allergic airway inflammation
Sammanfattning : Introduction: Asthma is a heterogeneous chronic lung disease associated with pronounced inflammatory changes in the airways. Eosinophilic inflammation is the trait that is best linked to symptoms and treatment responses in allergic asthma. LÄS MER