Sökning: "CCKB"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet CCKB.

  1. 1. Neuro-immune communication: role of the vagus nerve : an electrophysiological study

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Physiology and Pharmacology

    Författare :Violeta Bucinskaite; Karolinska Institutet.; Karolinska Institutet.; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cholecystokinin; CCKA; CCKB; cytokines; IL-1[beta]; illness; nerve activity; NIDDM; OLETF; the vagus; vagotomy;

    Sammanfattning : Defence mechanisms involve close interactions between the nervous and immune systems following an immune challenge. The vagal pathways which modulate major visceral functions under normal conditions are also important neural pathways for the transmission of information on peripheral conditions to the CNS. LÄS MER

  2. 2. Aspects on the psychopharmacology of cholecystokinin

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Clinical Neuroscience

    Författare :Diana Radu; Karolinska Institutet.; Karolinska Institutet.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cholecystokinin; brain; tripeptidyl-peptidase II; CCK receptors; schizophrenia; anxiety; stress; rat; monkey; human; pentagastrin; C-peptide; mRNA;

    Sammanfattning : This thesis includes studies of the effect of mild stress on brain cholecystokinin (CCK), anatomy of markers for CCK-ergic transmission in the brain and the systemic effect of CCK receptor stimulation in a clinical test for anxiety and fear. CCK is a brain-gut peptide acting as a neurotransmitter in mammalian brain via CCKA (CCK1) and CCKB (CCK2) receptors. LÄS MER

  3. 3. Peripherally administered choleocystokinin-8 increases neurotrophins in the brain

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Physiology and Pharmacology

    Författare :Paola Tirassa; Karolinska Institutet.; Karolinska Institutet.; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NGF; BDNF; CCK-8; glutamate; GABA; CCK receptors; hypothamalus; hippocampus; Choline Acetyltransferase; fimibria-fornix transection; vagotomy; vagal stimulation; RT-PCR; ELISA;

    Sammanfattning : The aim of this thesis was to test the hypothesis that the gastric hormone Cholecystokinin-8 (CCK-8) can modulate the production of Nerve Growth Factor (NGF) in the brain. NGF is the first discovered and the best characterized neurotrophic factor which plays a crucial role in the survival and development of basal forebrain cholinergic neurons (BFCN). LÄS MER

  4. 4. Neuropeptide circuitries regulating food and water intake

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Neuroscience

    Författare :Christian Broberger; Karolinska Institutet.; Karolinska Institutet.; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; agouti gene-related protein; anorexia mutation; arcuate nucleus; cholecystokinin; cocaine- and amphetamine-regulated transcript; coexistence; confocal microscopy; dorsal root ganglion; feeding; hypocretin; immunohistochemistry; in situ hybridization; melanin-concentrating hormone; nodose ganglion; nucleus tractus solitaxii; orexin; paraventricular nucleus; satiety; sensory neurones; pro-opiomelanocortin; vagus nerve;

    Sammanfattning : An adequate supply of nutrients through food intake is critical for survival, as evidenced by disorders such as obesity and anorexia, which in the long run may be lifethreatening. Feeding behaviour is ultimately controlled by interacting neuronal populations in the brain. LÄS MER

  5. 5. On the neuropeptide mRNA expression following neuropsychopharmacological treatments

    Detta är en avhandling från Stockholm : Karolinska Institutet, false

    Författare :Olof Zachrisson; Karolinska Institutet.; Karolinska Institutet.; [1998]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cholecystokinin; Excitotoxicity; Electroconvulsive; In situ hybridisation; Kainic acid; Lithium; Manic-depressive illness; Neuropeptide Y; Rat brain; Schizophrenia; Seizure; Somatostatin; Substance P; Tachykinin receptor;

    Sammanfattning : In addition to classical neurotransmitters, an increasing number of neuropeptides have been found in the brain. Although neuropeptides may play important roles especially in higher brain functions such as emotion, mood, memory, and learning, most focus has been directed upon classical neurotransmitters and their receptors. LÄS MER